ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation. - Wikidata - awgldk - TriplyDB

ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation.

ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation.

http://www.wikidata.org/entity/Q35894184

about

Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity Epigenome-guided analysis of the transcriptome of plaque macrophages during atherosclerosis regression reveals activation of the Wnt signaling pathway Cholesterol, inflammation and innate immunity High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.Cell-Type Specific Determinants of NRAMP1 Expression in Professional Phagocytes 25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.Mechanistic heterogeneity in site recognition by the structurally homologous DNA-binding domains of the ETS family transcription factors Ets-1 and PU.1.Epigenetic regulation of cholesterol homeostasis.Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux.Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation.Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112: Effects on Cholesterol Efflux, Anti-Inflammatory and Antioxidative Activity.An Empirical Prior Improves Accuracy for Bayesian Estimation of Transcription Factor Binding Site Frequencies within Gene Promoters.The intriguing ultrastructure of lipid body organelles within activated macrophages.KLF4 Regulation of Ch25h and LXR Mitigates Atherosclerosis Susceptibility.Runx2, a target gene for activating transcription factor-3 in human breast cancer cells.Activating transcription factor 3 interferes with p21 activation in histone deacetylase inhibitor-induced growth inhibition of epidermoid carcinoma cells.Exosomal ATF3 RNA attenuates pro-inflammatory gene MCP-1 transcription in renal ischemia-reperfusion.Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection.Glucocorticoid Induces Hepatic Steatosis by Inhibiting Activating Transcription Factor 3 (ATF3)/S100A9 Protein Signaling in Granulocytic Myeloid-derived Suppressor Cells.ATF3 negatively regulates cellular antiviral signaling and autophagy in the absence of type I interferons.Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis.Gut Microbial Metabolites Fuel Host Antibody Responses.Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis.Identifying novel transcription factors involved in the inflammatory response by using binding site motif scanning in genomic regions defined by histone acetylation.IL-27-Induced Type 1 Regulatory T-Cells Produce Oxysterols that Constrain IL-10 Production.Transcriptome Profiling in Systems Vascular Medicine Oxidized Low-Density Lipoprotein Loading of Macrophages Downregulates TLR-Induced Proinflammatory Responses in a Gene-Specific and Temporal Manner through Transcriptional Control.Anti-inflammatory effects of high-density lipoprotein through activating transcription factor 3: benefit beyond cholesterol transport-dependent processes Modulating Oxysterol Sensing to Control Macrophage Apoptosis and Atherosclerosis.25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism.Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet.Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice.Role of Aramchol in steatohepatitis and fibrosis in mice.

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ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol-induced lipid body formation.

http://www.wikidata.org/entity/Q35894184

description

2012 nî lūn-bûn

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2012年の論文

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Journal of Experimental Medicine

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ATF3 protects against atherosc ...... -induced lipid body formation.

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Alan Aderem

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David J Rodriguez

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Elizabeth S Gold

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Irina Podolsky

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Jyrki Selinummi

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Mark J Sartain

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Robert L Moritz

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Stephen A Ramsey

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P2860

Bright field microscopy as an alternative to whole cell fluorescence in automated analysis of macrophage images

Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data.

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Retinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodies

A simple method for the isolation and purification of total lipides from animal tissues

Summaries of Affymetrix GeneChip probe level data

Systems biology of innate immunity

Detection of functional DNA motifs via statistical over-representation

Macrophages in the pathogenesis of atherosclerosis

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10.1084/JEM.20111202

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4

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209

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223986425

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22473958

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atherosclerosis

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3328364

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