Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis. - Wikidata - awgldk - TriplyDB

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis.

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis.

http://www.wikidata.org/entity/Q41438930

about

The genetics and screening of familial hypercholesterolaemia Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity Infection homeostasis: implications for therapeutic and immune programming of metabolism in controlling infection An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway Viral MicroRNAs Repress the Cholesterol Pathway, and 25-Hydroxycholesterol Inhibits Infection.The citrus flavonoid naringenin confers protection in a murine endotoxaemia model through AMPK-ATF3-dependent negative regulation of the TLR4 signalling pathway Computational modelling of atherosclerosis.Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection.Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway.

P2860

Q26753081-195EAD2E-039F-4651-8807-5B9A2CDCD08E Q26800190-D31CFAE0-C22C-4CBB-BA11-A0F958C965ED Q28083186-08DE54C4-2418-4E37-9EA9-D989B3172D76 Q28550521-3DA9C6EE-1DEB-4605-89A1-D76729E58B0A Q33911258-824179F7-B4CB-4A24-ADEE-B5762C07C2BB Q37526079-F3EC6494-0DC4-4AB5-8C75-C512EA2F4404 Q38599711-90E9BC4E-8B88-453D-9FCF-1BA2B08B73AA Q39076009-5C6070D1-1AE4-4B16-8EFD-3E327956A7CF Q40046136-0F580CCB-2A6B-4DF0-ADB1-9E610AEFD93F

P2860

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis.

http://www.wikidata.org/entity/Q41438930

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Rapid proteasomal elimination ...... -hydroxycholesterol synthesis.

@en

type

label

Rapid proteasomal elimination ...... -hydroxycholesterol synthesis.

@en

prefLabel

Rapid proteasomal elimination ...... -hydroxycholesterol synthesis.

@en

P1433

Q41438930-C3F7012A-C504-4C13-A63D-EBF2664F251F

P1476

Q41438930-DAE71E01-7F8A-4B89-ABC6-6DBFD05428E0

P2093

Q41438930-575DD5C9-DC94-4497-93EE-60005B9D6BC6

Q41438930-5E48560F-1668-4981-B2F5-8CF3D044F1C6

Q41438930-88029244-74CC-4DB6-A10E-051915E148C4

Q41438930-A65D76F4-DF30-48CA-91E0-C4F4F807C5C2

P2860

Q41438930-03CFF658-11A4-45EA-BC3D-0D95591667AF

Q41438930-064DE9B5-8784-4390-98EB-B4648C4527B8

Q41438930-08AD0F74-855A-42B4-B42F-E45327D00FA8

Q41438930-11E85396-A556-4DC7-9BCC-B4B29DB6FD22

Q41438930-157C8CEC-DA83-440C-AF21-4DB526730A27

Q41438930-15902052-9ACD-41E4-94AD-8A129AAF7AFC

Q41438930-1B00FC7E-8156-4A55-A3C0-6A977AE79BDA

Q41438930-2224AA66-D555-47DE-9FAE-1DBE6AE83932

Q41438930-2593A374-A9BC-4ADE-B5F9-48FB883E23BD

Q41438930-283F7273-C293-4FF6-95D2-956A6B8548FF

P304

Q41438930-8B553D03-19E4-4D27-9251-EE66A44F89B3

P31

Q41438930-1CE016B5-FF3B-48D6-9F21-1034D2C7C223

P356

Q41438930-DC15BF56-3C30-4473-8E6B-543673ADCFAD

P433

Q41438930-600BFF09-9F4C-4605-99F0-B0467A548AB1

P478

Q41438930-71AAD7DC-200F-4AC5-A9C5-7DE3FCA85B77

P50

Q41438930-4ED32231-511D-4F81-B469-4553C481CC3F

Q41438930-986AF745-1BEE-48E2-9E8A-C6A59EF04BC8

Q41438930-9AE2FA2D-06F6-48BA-B916-8A415102379C

P577

Q41438930-0EB758CD-F856-4B8A-AD7E-E562CA3EB0B9

P5875

Q41438930-33A56065-4E24-42BC-A482-1AF77932DA85

P698

Q41438930-BFC08E8B-ABAB-47FD-BA39-1EA05CFAE1CC

P932

Q41438930-40856BE2-2361-44D1-9E64-FE9B36091783

P356

J.STEROIDS.2015.02.022

P1433

P1476

Rapid proteasomal elimination ...... -hydroxycholesterol synthesis.

@en

P2093

Douglas Roy

http://www.w3.org/2001/XMLSchema#string

Hongjin Lu

http://www.w3.org/2001/XMLSchema#string

Kevin A Robertson

http://www.w3.org/2001/XMLSchema#string

Simon Talbot

http://www.w3.org/2001/XMLSchema#string

P2860

Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL

Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles

Summaries of Affymetrix GeneChip probe level data

Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

P304

219-229

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.STEROIDS.2015.02.022

http://www.w3.org/2001/XMLSchema#string

P433

Pt B

http://www.w3.org/2001/XMLSchema#string

P478

99

http://www.w3.org/2001/XMLSchema#string

P50

Steven Watterson

Thorsten Forster

P577

2015-03-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

273261335

http://www.w3.org/2001/XMLSchema#string

P698

25759117

http://www.w3.org/2001/XMLSchema#string

P932

4503878

http://www.w3.org/2001/XMLSchema#string