Toward a molecular understanding of protein solubility: increased negative surface charge correlates with increased solubility
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What RNA World? Why a Peptide/RNA Partnership Merits Renewed Experimental AttentionAn experimental point of view on hydration/solvation in halophilic proteinsX-ray crystallographic validation of structure predictions used in computational design for protein stabilizationExpression of Functional Human Sialyltransferases ST3Gal1 and ST6Gal1 in Escherichia coliOptimized solubilization of TRIzol-precipitated protein permits Western blotting analysis to maximize data available from brain tissue.Coarse-grained model for colloidal protein interactions, B(22), and protein cluster formation.An extremely halophilic proteobacterium combines a highly acidic proteome with a low cytoplasmic potassium content.Evolution of mammalian diving capacity traced by myoglobin net surface charge.tRNA acceptor stem and anticodon bases form independent codes related to protein folding.Separating chemical and excluded volume interactions of polyethylene glycols with native proteins: Comparison with PEG effects on DNA helix formation.Enhanced production of a single domain antibody with an engineered stabilizing extra disulfide bondUltrahigh-throughput-directed enzyme evolution by absorbance-activated droplet sorting (AADS).Crystal structure and characterization of esterase Est25 mutants reveal improved enantioselectivity toward (S)-ketoprofen ethyl ester.Archaeal Inorganic Pyrophosphatase Displays Robust Activity under High-Salt Conditions and in Organic Solvents.All-atom molecular dynamics analysis of multi-peptide systems reproduces peptide solubility in line with experimental observationsLysine and arginine content of proteins: computational analysis suggests a new tool for solubility design.One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen.Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers.The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complexNon-peptide guided auto-secretion of recombinant proteins by super-folder green fluorescent protein in Escherichia coli.Introductory lecture: interpreting and predicting Hofmeister salt ion and solute effects on biopolymer and model processes using the solute partitioning modelBiocomposite nanofiber matrices to support ECM remodeling by human dermal progenitors and enhanced wound closure.Characterization of the translocation-competent complex between the Helicobacter pylori oncogenic protein CagA and the accessory protein CagF.Characterization of highly concentrated antibody solution - A toolbox for the description of protein long-term solution stabilityEffect of the surface charge distribution on the fluid phase behavior of charged colloids and proteins.Engineered solubility tag for solution NMR of proteins.Soluble expression of proteins correlates with a lack of positively-charged surface.Biophysical studies of protein solubility and amorphous aggregation by systematic mutational analysis and a helical polymerization model.Effect of molecular weight and ratio of poly ethylene glycols' derivatives in combination with trehalose on stability of freeze-dried IgG.Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation.Solubis: optimize your protein.Cytocompatible polyion complex gel of poly(Pro-Hyp-Gly) for simultaneous rat bone marrow stromal cell encapsulation.Protein charge determination and implications for interactions in cell extracts.Design of Self-Assembling Protein-Polymer Conjugates.Optimal charged mutations in the complementarity-determining regions that prevent domain antibody aggregation are dependent on the antibody scaffold.Computational analysis of the amino acid interactions that promote or decrease protein solubilityMolecular Modeling for Protein Aggregation and FormulationDiscovery and engineering of enhanced SUMO protease enzymes
P2860
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P2860
Toward a molecular understanding of protein solubility: increased negative surface charge correlates with increased solubility
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
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2012年论文
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2012年论文
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2012年论文
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name
Toward a molecular understandi ...... ates with increased solubility
@ast
Toward a molecular understandi ...... ates with increased solubility
@en
type
label
Toward a molecular understandi ...... ates with increased solubility
@ast
Toward a molecular understandi ...... ates with increased solubility
@en
prefLabel
Toward a molecular understandi ...... ates with increased solubility
@ast
Toward a molecular understandi ...... ates with increased solubility
@en
P2093
P2860
P1433
P1476
Toward a molecular understandi ...... ates with increased solubility
@en
P2093
C Nick Pace
J Martin Scholtz
Nicole Motl
Ryan M Kramer
Varad R Shende
P2860
P304
P356
10.1016/J.BPJ.2012.01.060
P407
P577
2012-04-01T00:00:00Z