Deciphering the molecular basis of memory failure in Alzheimer's disease.
about
Characterizing affinity epitopes between prion protein and β-amyloid using an epitope mapping immunoassayThe amyloid-beta precursor protein: integrating structure with biological function5-HT4 receptor agonists increase sAPPalpha levels in the cortex and hippocampus of male C57BL/6j miceAn epigenetic blockade of cognitive functions in the neurodegenerating brainReversing EphB2 depletion rescues cognitive functions in Alzheimer modelApoE promotes the proteolytic degradation of AbetaActive and passive immunotherapy for neurodegenerative disordersNeurodegeneration and microtubule dynamics: death by a thousand cutsPotential Therapeutical Contributions of the Endocannabinoid System towards Aging and Alzheimer's DiseaseThe Role of Ephs and Ephrins in Memory FormationElectrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomicsEphBs: an integral link between synaptic function and synaptopathiesAlzheimer's disease, amyloid peptide and synaptic dysfunctionLateral organization of the postsynaptic densityPrenatal activation of microglia induces delayed impairment of glutamatergic synaptic functionNeuronal seipin knockout facilitates Aβ-induced neuroinflammation and neurotoxicity via reduction of PPARγ in hippocampus of mouseStructural Correlates of Antibodies Associated with Acute Reversal of Amyloid -related Behavioral Deficits in a Mouse Model of Alzheimer DiseaseHuprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallographyRegulation of distinct pools of amyloid β-protein by multiple cellular proteasesNeuroprotective Mechanisms Mediated by CDK5 InhibitionA foldamer-dendrimer conjugate neutralizes synaptotoxic β-amyloid oligomersEssential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damageStructural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40) in Aqueous TrifluoroethanolCritical role of CDK5 and Polo-like kinase 2 in homeostatic synaptic plasticity during elevated activitySynaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formationEndocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's diseaseEphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomersDendritic spine pathology in neuropsychiatric disordersCortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's diseaseA β-amyloid oligomer directly modulates P/Q-type calcium currents in Xenopus oocytes.Molecular architecture of Aβ fibrils grown in cerebrospinal fluid solution and in a cell culture model of Aβ plaque formation.Protection against the synaptic targeting and toxicity of Alzheimer's-associated Aβ oligomers by insulin mimetic chiro-inositols.Epidermal growth factor receptor is a preferred target for treating amyloid-β-induced memory loss.Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptideDisruption of functional connectivity in clinically normal older adults harboring amyloid burden.Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network.Amyloid beta from axons and dendrites reduces local spine number and plasticity.Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production.Combination therapy in a transgenic model of Alzheimer's disease.Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling β-amyloid production.
P2860
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P2860
Deciphering the molecular basis of memory failure in Alzheimer's disease.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Deciphering the molecular basis of memory failure in Alzheimer's disease.
@ast
Deciphering the molecular basis of memory failure in Alzheimer's disease.
@en
type
label
Deciphering the molecular basis of memory failure in Alzheimer's disease.
@ast
Deciphering the molecular basis of memory failure in Alzheimer's disease.
@en
prefLabel
Deciphering the molecular basis of memory failure in Alzheimer's disease.
@ast
Deciphering the molecular basis of memory failure in Alzheimer's disease.
@en
P1433
P1476
Deciphering the molecular basis of memory failure in Alzheimer's disease.
@en
P2093
Dennis J Selkoe
Dominic M Walsh
P304
P356
10.1016/J.NEURON.2004.09.010
P407
P577
2004-09-01T00:00:00Z