Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.
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Therapeutics for Graft-versus-Host Disease: From Conventional Therapies to Novel Virotherapeutic StrategiesEZH2 in normal hematopoiesis and hematological malignanciesB cells in chronic graft-versus-host diseaseChromatin targeting drugs in cancer and immunityAcute graft-versus-host disease: a bench-to-bedside update.Longitudinal requirement for CD4+ T cell help for adenovirus vector-elicited CD8+ T cell responses.Histone demethylases UTX and JMJD3 are required for NKT cell development in miceHsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in miceEzh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice.Advances in graft-versus-host disease biology and therapy.EZH2 in normal and malignant hematopoiesis.3-Deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase, promotes erythroid differentiation.Epigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cellsHistone methylases as novel drug targets: developing inhibitors of EZH2.Advances in understanding the pathogenesis of graft-versus-host disease.Inhibition of histone methyltransferase EZH2 ameliorates early acute renal allograft rejection in ratsProgramming of donor T cells using allogeneic δ-like ligand 4-positive dendritic cells to reduce GVHD in mice.DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrityRole of EZH2 histone methyltrasferase in melanoma progression and metastasisThe histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host diseaseModulation of allogeneic CD8+ T-cell response by DZNep controls GVHD while preserving hematopoietic chimerism.Biology of graft-versus-host responses: recent insightsHistone methyltransferase and histone methylation in inflammatory T-cell responses.Next generation treatment of acute graft-versus-host disease.The Notch Ligand DLL4 Defines a Capability of Human Dendritic Cells in Regulating Th1 and Th17 Differentiation.Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity.EZH2 Impairs Human Dental Pulp Cell Mineralization via the Wnt/β-Catenin Pathway.Life and Death of Activated T Cells: How Are They Different from Naïve T Cells?Ezh2 Regulates Activation-Induced CD8+ T Cell Cycle Progression via Repressing Cdkn2a and Cdkn1c Expression.Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice.T-Cell Manipulation Strategies to Prevent Graft-Versus-Host Disease in Haploidentical Stem Cell Transplantation.
P2860
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P2860
Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Inhibition of histone methylat ...... alloreactive effector T cells.
@ast
Inhibition of histone methylat ...... alloreactive effector T cells.
@en
type
label
Inhibition of histone methylat ...... alloreactive effector T cells.
@ast
Inhibition of histone methylat ...... alloreactive effector T cells.
@en
prefLabel
Inhibition of histone methylat ...... alloreactive effector T cells.
@ast
Inhibition of histone methylat ...... alloreactive effector T cells.
@en
P2093
P2860
P1433
P1476
Inhibition of histone methylat ...... alloreactive effector T cells
@en
P2093
Arul M Chinnaiyan
Evelyn Nieves
Kazuhiro Mochizuki
Ram-Shankar Mani
Rork Kuick
Shin Mineishi
P2860
P304
P356
10.1182/BLOOD-2011-06-364422
P407
P577
2011-11-23T00:00:00Z