IL-21 is the primary common γ chain-binding cytokine required for human B-cell differentiation in vivo.
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IL-21 Signaling in ImmunityB-cell reconstitution for SCID: should a conditioning regimen be used in SCID treatment?The role of interleukin-21 in HIV infectionBMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5Hematopoietic stem cell transplantation for primary immunodeficiencies.The role of natural killer cells in pulmonary immunosurveillance.Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.IL2RG reversion event in a common lymphoid progenitor leads to delayed diagnosis and milder phenotype.Inborn errors of human JAKs and STATs.Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cellsIL-6 triggers IL-21 production by human CD4+ T cells to drive STAT3-dependent plasma cell differentiation in B cells.Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccineCCR7(lo)PD-1(hi) CXCR5(+) CD4(+) T cells are positively correlated with levels of IL-21 in active and transitional cystic echinococcosis patientsInducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 miceElevated Serum Levels of IL-21 in Kawasaki Disease.Post-transplantation B cell function in different molecular types of SCIDRole of IL-21 and IL-21 receptor on B cells in HIV infection.Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndromeInterleukin-21 overexpression dominates T cell response to Epstein-Barr virus in a fatal case of X-linked lymphoproliferative syndrome type 1Humanized mice, a new model to study the influence of drug treatment on neonatal sepsisPhenotypic and Functional Comparison of Class Switch Recombination Deficiencies with a Subgroup of Common Variable Immunodeficiencies.Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells.Evidence of innate lymphoid cell redundancy in humans.IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts.Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.Cytokine-Mediated Regulation of Plasma Cell Generation: IL-21 Takes Center Stage.Haematopoietic stem cell transplantation for SCID patients: where do we stand?Primary antibody deficiencies.Interleukin-21 and T follicular helper cells in HIV infection: research focus and future perspectives.Laboratory diagnosis of primary immunodeficiencies.Interleukin-21: a double-edged sword with therapeutic potential.Crosstalk Between T and B Cells in the Germinal Center After Transplantation.Human B-cell memory is shaped by age- and tissue-specific T-independent and GC-dependent events.Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant ConsortiumDifferences in Tfh Cell Response Between the Graft and Spleen With Chronic Allograft Nephropathy.Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies.Mutation in IRF2BP2 is responsible for a familial form of common variable immunodeficiency disorder.Longitudinal Evaluation of Immune Reconstitution and B-cell Function After Hematopoietic Cell Transplantation for Primary Immunodeficiency.In-depth determination and analysis of the human paired heavy- and light-chain antibody repertoire.Protection against Pertussis in Humans Correlates to Elevated Serum Antibodies and Memory B Cells
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P2860
IL-21 is the primary common γ chain-binding cytokine required for human B-cell differentiation in vivo.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
IL-21 is the primary common γ ...... -cell differentiation in vivo.
@ast
IL-21 is the primary common γ ...... -cell differentiation in vivo.
@en
type
label
IL-21 is the primary common γ ...... -cell differentiation in vivo.
@ast
IL-21 is the primary common γ ...... -cell differentiation in vivo.
@en
prefLabel
IL-21 is the primary common γ ...... -cell differentiation in vivo.
@ast
IL-21 is the primary common γ ...... -cell differentiation in vivo.
@en
P2093
P2860
P1433
P1476
IL-21 is the primary common γ ...... -cell differentiation in vivo.
@en
P2093
Andrew R Gennery
Danielle T Avery
Federica Cattaneo
Gillian A Tangye
Hans Oettgen
Hermann Eibel
Jane Peake
Jennifer M Puck
Joanne Smart
John B Ziegler
P2860
P304
P356
10.1182/BLOOD-2011-06-362533
P407
P577
2011-10-28T00:00:00Z