Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination
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A novel ARF-binding protein (LZAP) alters ARF regulation of HDM2Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2Cancer-associated mutations in the MDM2 zinc finger domain disrupt ribosomal protein interaction and attenuate MDM2-induced p53 degradationInvolvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ)The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligaseUbiquitination of human AP-endonuclease 1 (APE1) enhanced by T233E substitution and by CDK5.Identification and functional analysis of NOL7 nuclear and nucleolar localization signals.Post-translational regulation enables robust p53 regulation.p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion.Mutation of the zebrafish nucleoporin elys sensitizes tissue progenitors to replication stress.Discovery of novel proteasome inhibitors using a high-content cell-based screening systemPreimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway.Involvement of nuclear export in human papillomavirus type 18 E6-mediated ubiquitination and degradation of p53.Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor.High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis.Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation.Increased invasiveness and aggressiveness in breast epithelia with cytoplasmic p63 expression.Endoplasmic reticulum stress accelerates p53 degradation by the cooperative actions of Hdm2 and glycogen synthase kinase 3beta.Control of human PIRH2 protein stability: involvement of TIP60 and the proteosome.hGTSE-1 expression stimulates cytoplasmic localization of p53.Ubiquitin and ubiquitin-like proteins in the nucleolus: multitasking tools for a ribosome factory.Image cytometric analysis of p53 and mdm-2 expression in primary and recurrent mucoepidermoid carcinoma of parotid gland: immunohistochemical study.Cytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function.Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development.Splice-acceptor site mutation in p53 gene of hu888 zebrafish line.PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylationBAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function.Regulation of the protein stability of EMT transcription factorsPharmacologic activation of p53 by small-molecule MDM2 antagonistsInhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage.Aberrant p63 and WT-1 expression in myoepithelial cells of pregnancy-associated breast cancer: implications for tumor aggressiveness and invasivenessAging-associated truncated form of p53 interacts with wild-type p53 and alters p53 stability, localization, and activity.Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation.Regulation of p53--insights into a complex process.A novel oncoprotein Pirh2: rising from the shadow of MDM2.Phlda3, a urine-detectable protein, causes p53 accumulation in renal tubular cells injured by cisplatin.Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complexp53 Oligomerization is essential for its C-terminal lysine acetylation.Post-immunization immunohistochemical expression of Caspase 3 and p53 apoptotic markers in experimental hydatidosis.
P2860
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P2860
Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Nucleocytoplasmic shuttling of ...... adation but not ubiquitination
@ast
Nucleocytoplasmic shuttling of ...... adation but not ubiquitination
@en
type
label
Nucleocytoplasmic shuttling of ...... adation but not ubiquitination
@ast
Nucleocytoplasmic shuttling of ...... adation but not ubiquitination
@en
prefLabel
Nucleocytoplasmic shuttling of ...... adation but not ubiquitination
@ast
Nucleocytoplasmic shuttling of ...... adation but not ubiquitination
@en
P2093
P2860
P1476
Nucleocytoplasmic shuttling of ...... adation but not ubiquitination
@en
P2093
Huiping Li
Kevin O'Keefe
Yanping Zhang
P2860
P304
P356
10.1128/MCB.23.18.6396-6405.2003
P407
P577
2003-09-01T00:00:00Z