Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.
about
Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase.Effect of a monofunctional phenanthriplatin-DNA adduct on RNA polymerase II transcriptional fidelity and translesion synthesisDirect Characterization of Transcription Elongation by RNA Polymerase IThe fission yeast cytokinetic contractile ring regulates septum shape and closure.A genetic assay for transcription errors reveals multilayer control of RNA polymerase II fidelityStructural Model of RNA Polymerase II Elongation Complex with Complete Transcription Bubble Reveals NTP Entry RoutesDivergent contributions of conserved active site residues to transcription by eukaryotic RNA polymerases I and IITrigger loop folding determines transcription rate of Escherichia coli's RNA polymeraseTranscription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms.Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues.Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.Coliphage HK022 Nun protein inhibits RNA polymerase translocationControl of transcriptional elongation.Strand-specific (asymmetric) contribution of phosphodiester linkages on RNA polymerase II transcriptional efficiency and fidelity.Single molecule studies of RNA polymerase II transcription in vitro.Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase.A two-state model for the dynamics of the pyrophosphate ion release in bacterial RNA polymerase.Relationships of RNA polymerase II genetic interactors to transcription start site usage defects and growth in Saccharomyces cerevisiae.Five checkpoints maintaining the fidelity of transcription by RNA polymerases in structural and energetic details.DNA template dependent accuracy variation of nucleotide selection in transcription.Unfolding Kinetics of the Human Telomere i-Motif Under a 10 pN Force Imposed by the α-Hemolysin Nanopore Identify Transient Folded-State Lifetimes at Physiological pH.Activation and reactivation of the RNA polymerase II trigger loop for intrinsic RNA cleavage and catalysis.Eeny meeny miny moe, catch a transcript by the toe, or how to enumerate eukaryotic transcripts.High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.Mechanisms of backtrack recovery by RNA polymerases I and II.The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation.RNA polymerase stalls in a post-translocated register and can hyper-translocate.Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitutionEnergetic and structural details of the trigger-loop closing transition in RNA polymerase II.Relationships Between RNA Polymerase II Activity and Spt Elongation Factors to Spt- Phenotype and Growth in Saccharomyces cerevisiae.Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanismSingle molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activityDirect assessment of transcription fidelity by high-resolution RNA sequencing.Nucleosomal arrangement affects single-molecule transcription dynamics.Transcription factors IIS and IIF enhance transcription efficiency by differentially modifying RNA polymerase pausing dynamics.Molecular mechanisms of transcription through single-molecule experiments.Single-molecule studies of RNAPII elongation.Basic mechanism of transcription by RNA polymerase II.Basic mechanisms of RNA polymerase II activity and alteration of gene expression in Saccharomyces cerevisiae.
P2860
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P2860
Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Trigger loop dynamics mediate ...... nd speed of RNA polymerase II.
@ast
Trigger loop dynamics mediate ...... nd speed of RNA polymerase II.
@en
type
label
Trigger loop dynamics mediate ...... nd speed of RNA polymerase II.
@ast
Trigger loop dynamics mediate ...... nd speed of RNA polymerase II.
@en
prefLabel
Trigger loop dynamics mediate ...... nd speed of RNA polymerase II.
@ast
Trigger loop dynamics mediate ...... nd speed of RNA polymerase II.
@en
P2093
P2860
P50
P356
P1476
Trigger loop dynamics mediate ...... nd speed of RNA polymerase II.
@en
P2093
Matthew H Larson
Murali Palangat
Robert Landick
P2860
P304
P356
10.1073/PNAS.1200939109
P407
P577
2012-04-09T00:00:00Z