In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights.
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Quantitative distribution and colocalization of non-muscle myosin light chain kinase isoforms and cortactin in human lung endotheliumHDL-S1P: cardiovascular functions, disease-associated alterations, and therapeutic applicationsTonic regulation of vascular permeabilityActivation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier EnhancementSphingosine-1-phosphate as a mediator of high-density lipoprotein effects in cardiovascular protectionFTY720, an immunomodulatory sphingolipid mimetic: translation of a novel mechanism into clinical benefit in multiple sclerosisSphingosine-1-Phosphate Induces Dose-Dependent Chemotaxis or Fugetaxis of T-ALL Blasts through S1P1 ActivationPathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive AntagonismImproved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).Anti-angiogenic effect of tetraacetyl-phytosphingosine.Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesionsEssential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema.Sphingosine-1-Phosphate Treatment Can Ameliorate Microvascular Leakage Caused by Combined Alcohol Intoxication and Hemorrhagic Shock.Alphastatin downregulates vascular endothelial cells sphingosine kinase activity and suppresses tumor growth in nude mice bearing human gastric cancer xenografts.S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF.Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability.S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphateGene expression profiles of patients with cerebral hematoma following spontaneous intracerebral hemorrhage.Extracellular and intracellular actions of sphingosine-1-phosphateDifferential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung.Sphingosine-1-phosphate modulation of basal permeability and acute inflammatory responses in rat venular microvessels.Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules.Virus interactions with endothelial cell receptors: implications for viral pathogenesis.Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking.Genetic variants in Cell Adhesion Molecule 1 (CADM1): a validation study of a novel endothelial cell venous thrombosis risk factor.FTY720-phosphate is dephosphorylated by lipid phosphate phosphatase 3.Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation.Photolysis of caged sphingosine-1-phosphate induces barrier enhancement and intracellular activation of lung endothelial cell signaling pathways.Pharmacological relevance and potential of sphingosine 1-phosphate in the vascular system.Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic moleculesGlucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1.Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation.Attenuation by sphingosine-1-phosphate of rat microvessel acute permeability response to bradykinin is rapidly reversible.Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function.Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate.Nano-Biomechanical Study of Spatio-Temporal Cytoskeleton Rearrangements that Determine Subcellular Mechanical Properties and Endothelial PermeabilityErythrocyte-derived sphingosine-1-phosphate stabilizes basal hydraulic conductivity and solute permeability in rat microvessels.Reinforced Epithelial Barrier Integrity via Matriptase Induction with Sphingosine-1-Phosphate Did Not Result in Disturbances in Physiological Redox Status.Sphingosine 1-phosphate (S1P) carrier-dependent regulation of endothelial barrier: high density lipoprotein (HDL)-S1P prolongs endothelial barrier enhancement as compared with albumin-S1P via effects on levels, trafficking, and signaling of S1P1.Truth and consequences of sphingosine-1-phosphate lyase.
P2860
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P2860
In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
In vitro and in vivo modulatio ...... osphate: mechanistic insights.
@ast
In vitro and in vivo modulatio ...... osphate: mechanistic insights.
@en
type
label
In vitro and in vivo modulatio ...... osphate: mechanistic insights.
@ast
In vitro and in vivo modulatio ...... osphate: mechanistic insights.
@en
prefLabel
In vitro and in vivo modulatio ...... osphate: mechanistic insights.
@ast
In vitro and in vivo modulatio ...... osphate: mechanistic insights.
@en
P1433
P1476
In vitro and in vivo modulatio ...... osphate: mechanistic insights.
@en
P2093
Bryan J McVerry
Joe G N Garcia
P304
P356
10.1016/J.CELLSIG.2004.08.006
P577
2005-02-01T00:00:00Z