Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.
about
Structure and Substrate Recruitment of the Human Spindle Checkpoint Kinase Bub1In-silico modeling of the mitotic spindle assembly checkpointGenetic analysis of the spindle checkpoint genes san-1, mdf-2, bub-3 and the CENP-F homologues hcp-1 and hcp-2 in Caenorhabditis elegans.Loss of spindle assembly checkpoint-mediated inhibition of Cdc20 promotes tumorigenesis in mice.Monopolar spindle 1 (MPS1) kinase promotes production of closed MAD2 (C-MAD2) conformer and assembly of the mitotic checkpoint complexIn silico spatial simulations reveal that MCC formation and excess BubR1 are required for tight inhibition of the anaphase-promoting complex.Systems Biology Modeling of Five Pathways for Regulation and Potent Inhibition of the Anaphase-Promoting Complex (APC/C): Pivotal Roles for MCC and BubR1.The mitotic checkpoint complex (MCC): looking back and forth after 15 years.Mitotic Kinases and p53 Signaling.The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC.
P2860
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P2860
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.
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2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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name
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.
@ast
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.
@en
type
label
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.
@ast
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.
@en
prefLabel
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.
@ast
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint.
@en
P2860
P356
P1433
P1476
Running on a treadmill: dynamic inhibition of APC/C by the spindle checkpoint
@en
P2093
Hongtao Yu
P2860
P2888
P356
10.1186/1747-1028-2-23
P577
2007-07-24T00:00:00Z
P5875
P6179
1045651875