Canonical interaction of cyclin G associated kinase with adaptor protein 1 regulates lysosomal enzyme sorting
about
Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson diseaseUnbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson diseaseThe clathrin-binding and J-domains of GAK support the uncoating and chaperoning of clathrin by Hsc70 in the brainEndocytosis and clathrin-uncoating defects at synapses of auxilin knockout miceEssential role of cyclin-G-associated kinase (Auxilin-2) in developing and mature miceGenomewide association study for onset age in Parkinson disease.The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting.Functional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogasterDisruption of clathrin-mediated trafficking causes centrosome overduplication and senescence.Disruption of zebrafish cyclin G-associated kinase (GAK) function impairs the expression of Notch-dependent genes during neurogenesis and causes defects in neuronal development.Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.Oral Treatment with the Ghrelin Receptor Agonist HM01 Attenuates Cachexia in Mice Bearing Colon-26 (C26) TumorsSB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition.Bivalent Motif-Ear Interactions Mediate the Association of the Accessory Protein Tepsin with the AP-4 Adaptor Complex.AP-1 membrane-cytoplasm recycling regulated by mu1A-adaptin.Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study.Auxilin is required for formation of Golgi-derived clathrin-coated vesicles during Drosophila spermatogenesisAP-2-associated protein kinase 1 and cyclin G-associated kinase regulate hepatitis C virus entry and are potential drug targets.Combinatorial therapeutic activation with heparin and AICAR stimulates additive effects on utrophin A expression in dystrophic muscles.Eps15 mediates vesicle trafficking from the trans-Golgi network via an interaction with the clathrin adaptor AP-1.Auxilin depletion causes self-assembly of clathrin into membraneless cages in vivoSignaling circuits on the Golgi complex.Genes associated with Parkinson's disease: regulation of autophagy and beyond.The Potential Mutation of GAK Gene in the Typical Sporadic Parkinson's Disease from the Han Population of Chinese Mainland.Quantitative high-content imaging identifies novel regulators of Neo1 trafficking at endosomes.Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.A new hypothesis for Parkinson's disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics
P2860
Q22242985-170543CE-BA12-4EAC-837C-469D0D439B15Q24336432-0809576C-A8F4-4F08-AA3F-ACB0511B69DCQ28115999-F20040DA-D441-48BE-A385-B3A799F34973Q28119189-72F0668D-B3F1-42BF-95C8-536D3C7CBE0BQ28513312-EAEC855D-5738-4AD8-9652-4BCE25B51DF8Q29417034-85A78071-FEC1-4041-BCED-402C80EE5915Q29465779-EEDB4441-5A58-498E-BC36-F7C5A7393D95Q30492987-849B0223-AD8E-45D7-BEDA-FF136DDC6A53Q30560187-6232B29F-1B8D-4D4B-92AC-F30CF8CEE07EQ33524911-8B476611-BF0F-4E47-AFD1-8F15662F1AC8Q33630685-8EF7A2E1-B448-4565-A4C1-1F23235E5472Q33755034-1953042C-1B88-4406-AA68-0BDEE3668721Q33996875-3B86C4AA-C0B4-42BA-B63F-C9AB03C77716Q34500770-E598BFC1-1D49-4E6F-8DBD-5B5911BB284AQ34711471-4304006F-05AB-4DE5-8681-96663EA67F76Q34718087-AA50BEA6-2903-4E1C-B619-CA9115DCE87DQ35463368-A4F8437F-6FB5-4554-8DDC-4D6CD250BCD9Q35641039-75E88170-65ED-4E39-9585-B88585755402Q36402509-F477659A-9191-4C6B-9E8F-5C51E0F0C4BCQ36796883-4472BBF2-06B9-4D69-8B44-BC7C4F6863BEQ37066381-3B6FEDD4-3503-46C2-BC9A-C0A619E0A4F3Q38053208-29CDD50A-2968-4FB5-B0EE-5611E56C3C52Q38557027-16D6C8AE-D6BD-424D-A84D-F85C66842098Q40202718-446E0F00-B6ED-4DF4-B436-552F24528C4FQ41762405-B47232F9-AB28-41E3-82C9-3060D65A3F30Q51765180-BA8764DC-8C7B-454C-92AA-3BC38FE62F89Q58803163-73427789-9E65-4A41-9AA2-03238AAEF49D
P2860
Canonical interaction of cyclin G associated kinase with adaptor protein 1 regulates lysosomal enzyme sorting
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Canonical interaction of cycli ...... lates lysosomal enzyme sorting
@ast
Canonical interaction of cycli ...... lates lysosomal enzyme sorting
@en
type
label
Canonical interaction of cycli ...... lates lysosomal enzyme sorting
@ast
Canonical interaction of cycli ...... lates lysosomal enzyme sorting
@en
prefLabel
Canonical interaction of cycli ...... lates lysosomal enzyme sorting
@ast
Canonical interaction of cycli ...... lates lysosomal enzyme sorting
@en
P2093
P2860
P356
P1476
Canonical interaction of cycli ...... lates lysosomal enzyme sorting
@en
P2093
Evan Eisenberg
Kengo Moriyama
Lois E Greene
Patricia V Burgos
Rafael Mattera
Satoshi Kametaka
P2860
P304
P356
10.1091/MBC.E06-12-1162
P577
2007-05-30T00:00:00Z