Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency. - Wikidata - awgldk - TriplyDB

Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.

Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.

http://www.wikidata.org/entity/Q33630685

about

The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse Putative biomarkers and targets of estrogen receptor negative human breast cancer Yeast homologues of three BLOC-1 subunits highlight KxDL proteins as conserved interactors of BLOC-1.The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3.The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes.Biogenesis of lysosome-related organelles complex-1 subunit 1 (BLOS1) interacts with sorting nexin 2 and the endosomal sorting complex required for transport-I (ESCRT-I) component TSG101 to mediate the sorting of epidermal growth factor receptor int C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules.Gene dosage in the dysbindin schizophrenia susceptibility network differentially affect synaptic function and plasticity Cargo sorting to lysosome-related organelles regulates siRNA-mediated gene silencing.Analysis of tubulin alpha-1A/1B C-terminal tail post-translational poly-glutamylation reveals novel modification sites.Identification of Atg2 and ArfGAP1 as Candidate Genetic Modifiers of the Eye Pigmentation Phenotype of Adaptor Protein-3 (AP-3) Mutants in Drosophila melanogaster.Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1.Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene.Mechanisms of protein delivery to melanosomes in pigment cells.Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor.Snapin is critical for presynaptic homeostatic plasticity The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse The Intestinal Copper Exporter CUA-1 Is Required for Systemic Copper Homeostasis in Caenorhabditis elegans.Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus.Genomics and pharmacogenomics of schizophrenia.Genetic tests in major psychiatric disorders-integrating molecular medicine with clinical psychiatry-why is it so difficult?The BLOC-1 Subunit Pallidin Facilitates Activity-Dependent Synaptic Vesicle Recycling.An Eye on Trafficking Genes: Identification of Four Eye Color Mutations in Drosophila.Reduced expression of the dysbindin-like gene in the Bombyx mori ov mutant exhibiting mottled translucency of the larval skin.A homolog of the human Hermansky-Pudluck syndrome-5 (HPS5) gene is responsible for the oa larval translucent mutants in the silkworm, Bombyx mori.Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes.Biogenesis of zinc storage granules in Drosophila melanogaster.Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish.GCN5L1/BLOS1 Links Acetylation, Organelle Remodeling, and Metabolism.

P2860

02153f8ae20221f7e4921a6b60007e97491503ec 05dc28f303094891969b135475421e60de88da96 18e66c721c5bd387bb60920c31999fa9ad583c77 24d4acf596e89d8d2a8d6abb5ecaf3ec8b1c96b9 301b9f0aab592b810c4319673f37f8b51b3f2c06 31b6e1e08577792fb5ab53cfac5780e6fac0fc86 47031f1c9afbc1f4ff00c5a453155e2e0b6477a5 49e7e4fd4bd31792deba18c4a866618eb7d2a94b 4eec30418b5f7fbe81d137a8c8114759ec8f23cf 514e6d1f8b948c8a642fe5439dbb17d9e1f9d51e 538d149562b43b6e517ad651384ef93ec6de0f06 54963d7585ee2f0604bacadd542f554323646f57 581e007fd7f8ea23264e082a39111ef3ace888e9 5b9bff347c4cbee9c49f60c93a0d497dff41c730 5ec67f2dbc4b4e1a6d4a0f902be75b217486a6fb 5fcff4ecfd54bceee955d46e044d1fdf0e50e94f 6739ec65cbb8c0fe82238722f31c5922792ff076 6a6a6c86ea6c287abd6540cd15c61a714710eafc 7a58903b97d71e5a5914f149f50dbcd183baa4f1 7a873c0e8d9344eec1259b0a14f49305e22b2a6e 83fc903a11d78456941356f986b422e750f18937 847d4afa7b423ef713c7128388e08a04e7f8b531 8c2fa08bc974d65e9efd60a2c575bedeaae60fc5 942ebeca2898ba119d1e531b48f8a1d2e195cd66 9c50e3c85571d1967da61a381e0cc75432702193 b0edc0070bd9a596a56144c6b304838d2664345e bf7703aaedfdf660dfb0b2a0182fae999acd69e2 cccb247aca895508e0319fa043304fa6f6a1f59f def9faa5227505ba50f30b96522dc58a5e37846d ef875ffb4bd68ea4093523f232ea6d0d566294c3 f433ace3108b176a0897888d4de72ccf52bbe7e4 f6baa9cb05310c01383ffb5fea8e87714dc8fa4a

P248

Q24293250-2619044A-7FCF-4399-AD39-830E6A2672DD Q27003285-8A9CD01C-3835-43A4-B835-FE62B0BACFF4 Q27939848-4EF9A1DE-3962-4BA8-BA4E-40A6FA5D3191 Q27940067-5FB87549-7170-4743-9763-BFFFFC134349 Q28507551-88EA13FD-922C-4110-A7D8-59D49E234142 Q33619538-6BECB622-B09A-4452-8743-5612A13D32AD Q34355752-84627B4D-959D-4483-B2FB-F73C66E89962 Q34391252-92734B26-B0C4-4BD4-8298-CDC1B3E34654 Q34869759-90760D91-1FCB-44C3-9044-6FB6505AF9EB Q35102461-B7221562-4F0D-42CA-8B89-464E754E6F0D Q35798534-9F5F6702-9C14-4E63-8143-5B47872BB3A0 Q35840841-556B0D7C-F55F-431F-94B9-7A643644BE06 Q35856391-3560E301-CB36-45B5-ADA3-69CA87DE61B8 Q35875021-D93C6FC5-6820-4472-BD30-55AA9AF26D14 Q35936316-C7F56BA9-61E4-4580-963E-D67CA29F94C9 Q36065482-D39022A7-E387-4087-BBCE-E05A3D50FBAE Q36091712-0375465F-44DB-41FA-8BC4-689550EA3A22 Q37490360-E94CB450-D565-4F4B-8291-ACF14C68DF83 Q37567216-A1921B50-08CF-47FA-AC08-15E85F7A11D9 Q37692058-1AB6D935-DA95-4062-A6AE-0C32A90FCC85 Q37780792-40A3CA5E-93C2-4521-AC7C-8E3C27096904 Q38671562-EAAD097C-8A7B-4022-A9CF-9714FCD5659D Q38895201-73A0873B-0F1A-4F9D-AF12-F727099586E0 Q39455934-38B3178E-EBEE-4F41-B4EB-78CBEB9124BB Q42009142-15D1FB93-B533-4E64-8C88-D954CC5097BC Q42010544-687AA092-F8BC-4E41-A3F2-B3DCBF8690CC Q45976861-221D9195-96E3-4107-B556-44F23F827B6E Q48172700-526DB02C-A10D-4BB6-B380-F94E2F5244FD Q50020650-028AC02F-CFC2-4C7A-AF92-C50F3C45A99B Q52373412-11C72FB0-F9B4-4C7B-9666-B8C6B804E596

P2860

Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.

http://www.wikidata.org/entity/Q33630685

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Genetic modifiers of abnormal ...... la model of BLOC-1 deficiency.

@ast

Genetic modifiers of abnormal ...... la model of BLOC-1 deficiency.

@en

type

label

Genetic modifiers of abnormal ...... la model of BLOC-1 deficiency.

@ast

Genetic modifiers of abnormal ...... la model of BLOC-1 deficiency.

@en

prefLabel

Genetic modifiers of abnormal ...... la model of BLOC-1 deficiency.

@ast

Genetic modifiers of abnormal ...... la model of BLOC-1 deficiency.

@en

P1433

Q33630685-0182D6FA-50C6-44BA-A8A2-DADB950A2FD1

P1476

Q33630685-64C132FE-1F0D-4401-A02F-E965E4727F27

P2093

Q33630685-0FA61DAD-5798-44C4-8D9D-57714439E21F

Q33630685-3849842C-6B0A-4929-84F2-9E3AE52DCB4E

Q33630685-4CA5AC3C-D2A5-416A-8B6E-805F81BCE62C

Q33630685-6AB1C7AF-19C8-41F0-8358-A8E0D6DD8FC5

Q33630685-6BE331E2-9BCD-4C6B-A454-EC2B22615ED0

Q33630685-8707D33B-304A-4D98-B2D9-B3CE9E5B0FD0

Q33630685-975B11D7-6C0E-4936-9377-1C4A3FEC9E34

Q33630685-A6D54011-9AFF-445B-85CC-F9AA21277601

Q33630685-CC7589EF-446C-4B4D-BEE5-1E6A700D52E6

Q33630685-DB3E4DD0-DB61-4831-8A72-6FC461206EA3

P2860

Q33630685-0195FA1A-80BA-4C55-8589-FA5ACF200A0E

Q33630685-03B5FF40-022D-4369-A8D1-AE4EDF612845

Q33630685-04C6E50A-D28E-45AA-B81D-EC0DB0083A30

Q33630685-066AE25C-0FC6-4ED0-A995-8A6AC6E2E8D9

Q33630685-06BA07D1-3FFD-4F29-B889-7A7A6FD63F53

Q33630685-08860D02-9D3E-481C-B8AE-0FAFDA7C211C

Q33630685-0957FDBB-9DF5-46DF-9C89-BF877667F439

Q33630685-09FDA2FF-2815-4D98-AC2B-79EBFC22801D

Q33630685-0FC54077-B32A-429C-9C97-0EEAB7D9A0CA

Q33630685-1A0704A5-C9EA-4DA5-B198-4072C2A5C756

P304

Q33630685-F6440DB2-60A7-4455-B413-A48F53BACD8F

P31

Q33630685-300AAF35-1E3E-4C44-BA72-CE4F69BF3B20

P356

Q33630685-11594DFD-9AB4-433D-9C0A-CFDA4D1532EE

P433

Q33630685-7E980E56-9E81-4389-9087-33D0FECF12BA

P478

Q33630685-87200566-ACD6-4554-AABA-422660F3D611

P50

Q33630685-2315C227-ECCA-4ADE-9A26-C1573E728745

Q33630685-D48E713F-A3FE-4F98-B8AD-B5759D15A691

P577

Q33630685-3F143B78-FAD8-4F65-A113-551035BBFC00

P5875

Q33630685-B6F81085-B68A-467C-9923-6DFE7C7E9908

P698

Q33630685-3CCDD1F5-D293-4ACE-9045-7E52DE702807

P921

Q33630685-E171052A-D8F0-4A83-9534-0B7DB64DFDAC

P932

Q33630685-8EA3B383-DEFD-4497-A631-C21603B1E1FA

P356

P1433

Human Molecular Genetics

P1476

Genetic modifiers of abnormal ...... ila model of BLOC-1 deficiency

@en

P2093

Aaron DiAntonio

http://www.w3.org/2001/XMLSchema#string

David E Krantz

http://www.w3.org/2001/XMLSchema#string

Diego J Hoyle

http://www.w3.org/2001/XMLSchema#string

Esteban C Dell'Angelica

http://www.w3.org/2001/XMLSchema#string

Henry C Chang

http://www.w3.org/2001/XMLSchema#string

Marta Starcevic

http://www.w3.org/2001/XMLSchema#string

Richard W Daniels

http://www.w3.org/2001/XMLSchema#string

Ruth Godoy

http://www.w3.org/2001/XMLSchema#string

Stephen Poole

http://www.w3.org/2001/XMLSchema#string

Vasundhara Kandachar

http://www.w3.org/2001/XMLSchema#string

P2860

Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor

AP-3 mediates tyrosinase but not TRP-1 trafficking in human melanocytes

BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules

A germline mutation in BLOC1S3/reduced pigmentation causes a novel variant of Hermansky-Pudlak syndrome (HPS8)

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis

Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes

Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)

BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles

The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth

P304

861-878

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/HMG/DDP555

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

19

http://www.w3.org/2001/XMLSchema#string

P50

Julian Martinez-agosto

P577

2009-12-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

40693335

http://www.w3.org/2001/XMLSchema#string

P698

20015953

http://www.w3.org/2001/XMLSchema#string

P921

P932

2816613

http://www.w3.org/2001/XMLSchema#string