p53 mediates senescence-like arrest induced by chronic replicational stress
about
Mnk kinase pathway: Cellular functions and biological outcomesPolyoma small T antigen triggers cell death via mitotic catastropheSmall molecule compounds that induce cellular senescenceInterference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaksA reduction of licensed origins reveals strain-specific replication dynamics in miceExtracellular vesicles secreted from cancer cell lines stimulate secretion of MMP-9, IL-6, TGF-β1 and EMMPRINIrradiation selects for p53-deficient hematopoietic progenitors.Wnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl.Hydroxycarbamide: a user's guide for chronic myeloproliferative disorders.Stable cellular senescence is associated with persistent DDR activationLoss of DNA polymerase zeta enhances spontaneous tumorigenesis.Senescence and apoptosis: dueling or complementary cell fates?The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?Induction of cancerous stem cells during embryonic stem cell differentiation.Replicational stress selects for p53 mutationTelomeric DNA damage is irreparable and causes persistent DNA-damage-response activationCommon Chemical Inductors of Replication Stress: Focus on Cell-Based Studies.Deoxyribonucleotide metabolism, mutagenesis and cancer.DNA-damage response in hematopoietic stem cells: an evolutionary trade-off between blood regeneration and leukemia suppression.Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen.Differential regulation of FBXW7 isoforms by various stress stimuli.Could stress granules be involved in age-related diseases?Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress.DNA replication stress and cancer chemotherapy.Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status.A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia.Significance of cellular senescence in aging and cancer.Transcriptional activation of p21Waf1 contributes to suppression of HR by p53 in response to replication arrest induced by camptothecin.
P2860
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P2860
p53 mediates senescence-like arrest induced by chronic replicational stress
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
p53 mediates senescence-like arrest induced by chronic replicational stress
@ast
p53 mediates senescence-like arrest induced by chronic replicational stress
@en
type
label
p53 mediates senescence-like arrest induced by chronic replicational stress
@ast
p53 mediates senescence-like arrest induced by chronic replicational stress
@en
prefLabel
p53 mediates senescence-like arrest induced by chronic replicational stress
@ast
p53 mediates senescence-like arrest induced by chronic replicational stress
@en
P2093
P2860
P356
P1476
p53 mediates senescence-like arrest induced by chronic replicational stress
@en
P2093
Andriy Marusyk
Christopher K Mathews
James DeGregori
Linda J Wheeler
P2860
P304
P356
10.1128/MCB.01316-06
P407
P577
2007-05-21T00:00:00Z