Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.
about
c-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and -dependent mechanismsThe emerging roles of β-arrestins in fibrotic diseasesRegulation of CaMKII signaling in cardiovascular diseaseBiased and g protein-independent signaling of chemokine receptorsCell-surface receptors transactivation mediated by g protein-coupled receptorsTargeting G protein coupled receptor-related pathways as emerging molecular therapiesThe relationship between the MMP system, adrenoceptors and phosphoprotein phosphatasesGene therapy targets in heart failure: the path to translationNuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signalingCrystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and CarvedilolBeta-arrestins: multifunctional cellular mediatorsMitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.Identification of gene signatures regulated by carvedilol in mouse heartImpedance responses reveal β₂-adrenergic receptor signaling pluridimensionality and allow classification of ligands with distinct signaling profilesIndependent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptorThe EGFR tyrosine kinase inhibitor tyrphostin AG-1478 causes hypomagnesemia and cardiac dysfunctionArresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4PDK1 coordinates survival pathways and beta-adrenergic response in the heartActivation of a novel estrogen receptor, GPER, is cardioprotective in male and female ratsThe expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development.G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.Src is required for mechanical stretch-induced cardiomyocyte hypertrophy through angiotensin II type 1 receptor-dependent β-arrestin2 pathways.β-Adrenergic receptor-mediated transactivation of epidermal growth factor receptor decreases cardiomyocyte apoptosis through differential subcellular activation of ERK1/2 and Akt.β-adrenergic receptor-dependent alterations in murine cardiac transcript expression are differentially regulated by gefitinib in vivoEpidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular Systemβ-Adrenergic receptor subtype signaling in heart: from bench to bedside.beta-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation.Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion.Beyond desensitization: physiological relevance of arrestin-dependent signaling.Autotaxin-lysophosphatidic acid-LPA3 signaling at the embryo-epithelial boundary controls decidualization pathwaysA G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate.Teaching old receptors new tricks: biasing seven-transmembrane receptors.Troglitazone stimulates beta-arrestin-dependent cardiomyocyte contractility via the angiotensin II type 1A receptor.Distinct roles of arrestin 1 protein in photoreceptors during Drosophila developmentThe chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation.Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development.Regulation of GPCR signaling in hypertension.Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch.Functional selectivity in adrenergic and angiotensin signaling systems.
P2860
Q24317611-E167A3B5-6575-441F-B017-D6F7505AF828Q26783047-C3CDAC95-2C4E-4DC1-B304-0D8C3651A2D2Q26785302-A9E545B1-47F4-4EDF-811B-9BDEF1F15FB0Q26823970-E43391C5-B109-4077-BC63-2B385240159DQ26827583-51B8C388-4A4B-4F34-9E76-FD2A5493A6A9Q26829964-D1E9514E-24A5-47B1-B266-F354807C7472Q27003263-45D7CEE1-2BC7-4E47-BACF-ACC96BA12BFEQ27022444-5C42CA59-4D5A-42DB-9FEF-7C3DFB13F973Q27026973-BC8C8481-222E-4590-B703-2BDA60998C8FQ27679036-124A7F7E-B56C-43CC-9292-EFEEBB373403Q28268438-831D3340-36A8-44CA-99FA-C844DE376B03Q28296128-75972749-DBC8-415A-B629-A9E0588D7D76Q28387435-CEE1E83D-A022-4BBE-959F-CD368D673DE0Q28478728-4708938A-5375-4A6F-811E-2B8895E89AFDQ28572837-B7EFF5E5-DE06-4AB2-805B-7ECEA788EEA7Q28581198-C880309B-2C1B-4FCA-993A-480CD9E4D80AQ28582124-2BA7EF42-2025-484F-AB68-88F756866094Q28585494-AF51785C-E0FA-47C8-8864-73CBD82CC606Q29347039-46380F46-06F5-44E1-88A7-79C94088DA30Q30250314-5BAB04FB-FDE8-4CA8-83E7-F63B26EA31DBQ30487539-CCF50109-0C15-4191-9787-4197315747E4Q30577637-BB848105-5CB9-4688-8A5C-066FD2F697A1Q31156054-16187615-14F1-4B04-B69F-FE34091EFA4EQ33680497-EABCB1AC-B43E-4F85-9D61-AF26EA1F7EB8Q33717215-A58EA328-D8EF-4383-8548-778D9722C646Q33814199-D07F415A-5231-42D9-BBDE-8C9FC6FD1FC4Q33828730-076D2854-422D-463A-AD36-0670D717E89CQ33840022-FDE118D5-D5B5-4800-9F25-EEBF1D6725CAQ33870552-80EED0C8-53CC-42A1-A73B-9FD9043A358EQ33890802-9E3B4522-9F81-4482-84E9-72A329E874B0Q33903608-5BF4EA3D-6964-4342-9D5D-BBC91FD9987DQ33948589-0746B43F-C487-4FEA-9887-CCB620AE0A1FQ33985759-98FDA5AA-1B06-4FB9-BC85-B8E10E9837A8Q34007211-7DFD7893-150B-4D8A-AC5E-4CC2518D56DAQ34074005-D7C3982A-7559-4776-8AA6-DC6A53AD517DQ34203682-4107F8B3-4615-494F-A471-B2023FE33519Q34249070-236D2AE4-65D0-4815-9686-2453F7086F8EQ34273837-6ABABDC2-C837-45C8-9502-300F61977801Q34317331-8C5CA824-75FE-4C90-B2EE-7720AB4B543FQ34359586-317C6A09-0EA4-4BC6-9A6B-378800DB38B0
P2860
Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Beta-arrestin-mediated beta1-a ...... EGFR confers cardioprotection.
@ast
Beta-arrestin-mediated beta1-a ...... EGFR confers cardioprotection.
@en
type
label
Beta-arrestin-mediated beta1-a ...... EGFR confers cardioprotection.
@ast
Beta-arrestin-mediated beta1-a ...... EGFR confers cardioprotection.
@en
prefLabel
Beta-arrestin-mediated beta1-a ...... EGFR confers cardioprotection.
@ast
Beta-arrestin-mediated beta1-a ...... EGFR confers cardioprotection.
@en
P2093
P2860
P356
P1476
Beta-arrestin-mediated beta1-a ...... EGFR confers cardioprotection
@en
P2093
Anthony Lemaire
Douglas G Tilley
Howard A Rockman
Huijun Wei
Jonathan D Violin
Juhsien Chen
Liza Barki-Harrington
Robert J Lefkowitz
Sathyamangla V Naga Prasad
Takahisa Noma
P2860
P304
P356
10.1172/JCI31901
P407
P577
2007-09-01T00:00:00Z