Expression of nuclear insulin receptor substrate 1 in breast cancer.
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IRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumorsAkt2 inhibition enables the forkhead transcription factor FoxO3a to have a repressive role in estrogen receptor alpha transcriptional activity in breast cancer cells.Insulin receptor substrates (IRSs) and breast tumorigenesis.Membrane localization of insulin receptor substrate-2 (IRS-2) is associated with decreased overall survival in breast cancerNuclear IRS-1 predicts tamoxifen response in patients with early breast cancer.IL4 receptor ILR4α regulates metastatic colonization by mammary tumors through multiple signaling pathwaysInsulin receptor substrate 2-mediated phosphatidylinositol 3-kinase signaling selectively inhibits glycogen synthase kinase 3β to regulate aerobic glycolysis.Altered gene expression patterns during the initiation and promotion stages of neonatally diethylstilbestrol-induced hyperplasia/dysplasia/neoplasia in the hamster uterus.Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins.Insulin receptor substrate-2 regulates aerobic glycolysis in mouse mammary tumor cells via glucose transporter 1.Expression and function of the insulin receptor substrate proteins in cancerTargeting the insulin-like growth factor 1 receptor (IGF1R) signaling pathway for cancer therapy.Nuclear IRS-1 and cancerDifferential involvement of the microtubule cytoskeleton in insulin receptor substrate 1 (IRS-1) and IRS-2 signaling to AKT determines the response to microtubule disruption in breast carcinoma cells.miR-106a* inhibits the proliferation of renal carcinoma cells by targeting IRS-2.High glucose and high insulin conditions promote MCF‑7 cell proliferation and invasion by upregulating IRS1 and activating the Ras/Raf/ERK pathway.IRS1/β-Catenin Axis Is Activated and Induces MYC Expression in Acute Lymphoblastic Leukemia Cells.Identification of a novel invasion-promoting region in Insulin Receptor Substrate 2 (IRS2).IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View.Pharmacophore modeling for identification of anti-IGF-1R drugs and in-vitro validation of fulvestrant as a potential inhibitor.
P2860
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P2860
Expression of nuclear insulin receptor substrate 1 in breast cancer.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Expression of nuclear insulin receptor substrate 1 in breast cancer.
@ast
Expression of nuclear insulin receptor substrate 1 in breast cancer.
@en
type
label
Expression of nuclear insulin receptor substrate 1 in breast cancer.
@ast
Expression of nuclear insulin receptor substrate 1 in breast cancer.
@en
prefLabel
Expression of nuclear insulin receptor substrate 1 in breast cancer.
@ast
Expression of nuclear insulin receptor substrate 1 in breast cancer.
@en
P2093
P2860
P50
P356
P1476
Expression of nuclear insulin receptor substrate 1 in breast cancer.
@en
P2093
Emilia Middea
Eva Surmacz
Filomena Casaburi
Francesco Romeo
Lucio Morabito
Sebastiano Andò
P2860
P304
P356
10.1136/JCP.2006.039107
P407
P577
2006-08-01T00:00:00Z