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Conserved CTCF insulator elements flank the mouse and human beta-globin lociThe insulation of genes from external enhancers and silencing chromatin.A chromatin insulator-like element in the herpes simplex virus type 1 latency-associated transcript region binds CCCTC-binding factor and displays enhancer-blocking and silencing activities.Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formationConservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genesGoat uromodulin promoter directs kidney-specific expression of GFP gene in transgenic miceCurrent and future alternative therapies for beta-thalassemia majorTransgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance.Characterization of inducible models of Tay-Sachs and related diseaseCTCF: making the right connectionsInsulators: exploiting transcriptional and epigenetic mechanismsAn Optimized GD2-Targeting Retroviral Cassette for More Potent and Safer Cellular Therapy of Neuroblastoma and Other CancersChromosomal proteins HMGN3a and HMGN3b regulate the expression of glycine transporter 1Direct identification of insulator components by insertional chromatin immunoprecipitationMutagenesis in rodents using the L1 retrotransposonIdentification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome.5'HS5 of the human beta-globin locus control region is dispensable for the formation of the beta-globin active chromatin hub.Overexpression of the mitochondrial T3 receptor p43 induces a shift in skeletal muscle fiber typesComparison of insulators and promoters for expression of the Wiskott-Aldrich syndrome protein using lentiviral vectors.Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrantsThe impact of local genome sequence on defining heterochromatin domains.Gene specificity of suppression of transgene-mediated insertional transcriptional activation by the chicken HS4 insulator.The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity.VEZF1 elements mediate protection from DNA methylation.Intergenic, gene terminal, and intragenic CpG islands in the human genome.Genomic approaches uncover increasing complexities in the regulatory landscape at the human SCL (TAL1) locus.Stem cell gene therapy for the beta-chain hemoglobinopathies. Problems and progress.The establishment of active chromatin domains.Complete biallelic insulation at the H19/Igf2 imprinting control region position results in fetal growth retardation and perinatal lethalityA functional screen for regulatory elements that improve retroviral vector gene expressionGenomic and functional assays demonstrate reduced gammaretroviral vector genotoxicity associated with use of the cHS4 chromatin insulator.Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element.Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3'LTR.Generation of adenovirus vectors devoid of all viral genes by recombination between inverted repeatsBAC TG-EMBED: one-step method for high-level, copy-number-dependent, position-independent transgene expression.Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integritySHP2E76K mutant promotes lung tumorigenesis in transgenic micePosition-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities.A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human T cells.Sequences sufficient for programming imprinted germline DNA methylation defined.
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Characterization of the chicken beta-globin insulator
@ast
Characterization of the chicken beta-globin insulator
@en
type
label
Characterization of the chicken beta-globin insulator
@ast
Characterization of the chicken beta-globin insulator
@en
prefLabel
Characterization of the chicken beta-globin insulator
@ast
Characterization of the chicken beta-globin insulator
@en
P2093
P2860
P356
P1476
Characterization of the chicken beta-globin insulator
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.2.575
P407
P577
1997-01-01T00:00:00Z