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Aurora B expression correlates with aggressive behaviour in glioblastoma multiformeNon-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell DivisionRecent advances in the development of Aurora kinases inhibitors in hematological malignanciesPossible Role of Aurora-C in MeiosisCell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition.Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configurationCrystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug designDevelopment of o -Chlorophenyl Substituted Pyrimidines as Exceptionally Potent Aurora Kinase InhibitorsCrystal Structure of Human Aurora B in Complex with INCENP and VX-680A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora AGL-1196 Suppresses the Proliferation and Invasion of Gastric Cancer Cells via Targeting PAK4 and Inhibiting PAK4-Mediated Signaling PathwaysEvolution of resistance to Aurora kinase B inhibitors in leukaemia cellsAurora-A kinase is essential for bipolar spindle formation and early developmentInhibition of Aurora kinase B is important for biologic activity of the dual inhibitors of BCR-ABL and Aurora kinases R763/AS703569 and PHA-739358 in BCR-ABL transformed cellsTreating adults with acute lymphocytic leukemia: new pharmacotherapy options.Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells.Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis.Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular functionSignificance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC.Molecular profiling of platinum resistant ovarian cancer.Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival.Identification of small molecule inhibitors of the mitotic kinase haspin by high-throughput screening using a homogeneous time-resolved fluorescence resonance energy transfer assay.A phase I schedule dependency study of the aurora kinase inhibitor MSC1992371A in combination with gemcitabine in patients with solid tumors.A phase l study of three different dosing schedules of the oral aurora kinase inhibitor MSC1992371A in patients with solid tumors.Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases.Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia.Global gene expression profiling of human pleural mesotheliomas: identification of matrix metalloproteinase 14 (MMP-14) as potential tumour targetA current review of targeted therapeutics for ovarian cancer.Differential expression of centrosomal proteins at different stages of human gliomaA phase I dose-escalation study of danusertib (PHA-739358) administered as a 24-hour infusion with and without granulocyte colony-stimulating factor in a 14-day cycle in patients with advanced solid tumors.Targeting high Aurora kinases expression as an innovative therapy for hepatocellular carcinoma.Mechanisms of the anti-tumor activity of Methyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo[d]imidazole-5-carboxylate against breast cancer in vitro and in vivoAntineoplastic effects of an Aurora B kinase inhibitor in breast cancer.Current progress and future perspectives in the development of anti-polo-like kinase 1 therapeutic agents.Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation.P-glycoprotein and breast cancer resistance protein in acute myeloid leukaemia cells treated with the aurora-B kinase inhibitor barasertib-hQPAInhibition of Aurora-B suppresses HepG2 cell invasion and migration via the PI3K/Akt/NF-κB signaling pathway in vitroBeyond taxanes: a review of novel agents that target mitotic tubulin and microtubules, kinases, and kinesins.SUMOylation modulates the function of Aurora-B kinase
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Aurora-kinase inhibitors as anticancer agents.
@ast
Aurora-kinase inhibitors as anticancer agents.
@en
type
label
Aurora-kinase inhibitors as anticancer agents.
@ast
Aurora-kinase inhibitors as anticancer agents.
@en
prefLabel
Aurora-kinase inhibitors as anticancer agents.
@ast
Aurora-kinase inhibitors as anticancer agents.
@en
P2860
P356
P1476
Aurora-kinase inhibitors as anticancer agents.
@en
P2093
Nicholas Keen
Stephen Taylor
P2860
P2888
P304
P356
10.1038/NRC1502
P407
P577
2004-12-01T00:00:00Z
P5875
P6179
1007682820