Coupling of retinal isomerization to the activation of rhodopsin.
about
Potential modes of interaction of 9-aminomethyl-9,10-dihydroanthracene (AMDA) derivatives with the 5-HT2A receptor: a ligand structure-affinity relationship, receptor mutagenesis and receptor modeling investigationPlasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuSTwo-dimensional solid-state NMR applied to a chimeric potassium channel.Unraveling the structure and function of G protein-coupled receptors through NMR spectroscopy.Molecular simulations and solid-state NMR investigate dynamical structure in rhodopsin activation.Membrane protein structure and dynamics from NMR spectroscopy.G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy.Retinal ligand mobility explains internal hydration and reconciles active rhodopsin structuresMicrosecond time-resolved circular dichroism of rhodopsin photointermediates.Temperature dependence of the lumirhodopsin I-lumirhodopsin II equilibriumModeling activated states of GPCRs: the rhodopsin template.How a small change in retinal leads to G-protein activation: initial events suggested by molecular dynamics calculations.Retinal conformation and dynamics in activation of rhodopsin illuminated by solid-state H NMR spectroscopy.Sequential rearrangement of interhelical networks upon rhodopsin activation in membranes: the Meta II(a) conformational substate.Comparison of class A and D G protein-coupled receptors: common features in structure and activation.Location of the retinal chromophore in the activated state of rhodopsin*.Solid-state 2H NMR relaxation illuminates functional dynamics of retinal cofactor in membrane activation of rhodopsinG protein-coupled receptor rhodopsin.Local peptide movement in the photoreaction intermediate of rhodopsin.Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators.Novel rhodopsin mutations and genotype-phenotype correlation in patients with autosomal dominant retinitis pigmentosa.Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes.Role of group-conserved residues in the helical core of beta2-adrenergic receptorIdentification of motions in membrane proteins by elastic network models and their experimental validation.Mechanism of signal propagation upon retinal isomerization: insights from molecular dynamics simulations of rhodopsin restrained by normal modesProton movement and photointermediate kinetics in rhodopsin mutantsAtomistic insights into rhodopsin activation from a dynamic modelSolid-state 2H NMR spectroscopy of retinal proteins in aligned membranes.Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation.Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation.Conformational states and dynamics of rhodopsin in micelles and bilayers.Structural analysis and dynamics of retinal chromophore in dark and meta I states of rhodopsin from 2H NMR of aligned membranes.Retinal dynamics during light activation of rhodopsin revealed by solid-state NMR spectroscopy.CONDENSED-MATTER SPECTROSCOPY SPECTRAL METHODS FOR STUDY OF THE G-PROTEIN-COUPLED RECEPTOR RHODOPSIN. II. MAGNETIC RESONANCE METHODS.Microbial and animal rhodopsins: structures, functions, and molecular mechanisms.NMR in natural products: understanding conformation, configuration and receptor interactions.SPECTRAL METHODS FOR STUDY OF THE G-PROTEIN-COUPLED RECEPTOR RHODOPSIN. I. VIBRATIONAL AND ELECTRONIC SPECTROSCOPY.High-resolution NMR spectroscopy of a GPCR in aligned bicelles.A pivot between helices V and VI near the retinal-binding site is necessary for activation in rhodopsins.Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure.
P2860
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P2860
Coupling of retinal isomerization to the activation of rhodopsin.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Coupling of retinal isomerization to the activation of rhodopsin.
@ast
Coupling of retinal isomerization to the activation of rhodopsin.
@en
type
label
Coupling of retinal isomerization to the activation of rhodopsin.
@ast
Coupling of retinal isomerization to the activation of rhodopsin.
@en
prefLabel
Coupling of retinal isomerization to the activation of rhodopsin.
@ast
Coupling of retinal isomerization to the activation of rhodopsin.
@en
P2093
P2860
P356
P1476
Coupling of retinal isomerization to the activation of rhodopsin.
@en
P2093
Amiram Hirshfeld
Ashish B Patel
Evan Crocker
Markus Eilers
Mordechai Sheves
Steven O Smith
P2860
P304
10048-10053
P356
10.1073/PNAS.0402848101
P407
P577
2004-06-25T00:00:00Z