Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency. - Wikidata - awgldk - TriplyDB

Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency.

Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency.

http://www.wikidata.org/entity/Q35992006

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Functional Mechanisms of Treg in the Context of HIV Infection and the Janus Face of Immune Suppression Ubiquitin-dependent regulation of Foxp3 and Treg function Aryl hydrocarbon receptor control of adaptive immunity Treg functional stability and its responsiveness to the microenvironment The Ikaros family of zinc-finger proteins Histone Posttranslational Modifications of CD4⁺ T Cell in Autoimmune Diseases The role of epigenetic mechanisms and processes in autoimmune disorders Epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional suppression of Tregs.Vagaries of fluorochrome reporter gene expression in Foxp3+ regulatory T cells.Once a Treg, always a Treg?Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses Ubiquitous points of control over regulatory T cells.Rapid rebound of the Treg compartment in DEREG mice limits the impact of Treg depletion on mycobacterial burden, but prevents autoimmunity Appropriate development of the liver Treg compartment is modulated by the microbiota and requires TGF-β and MyD88.PD-1 regulates extrathymic regulatory T-cell differentiation.Master regulators or lineage-specifying? Changing views on CD4+ T cell transcription factors Ischemic preconditioning in the liver is independent of regulatory T cell activity.Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse Epigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cells Modification of the FoxP3 transcription factor principally affects inducible T regulatory cells in a model of experimental autoimmune encephalomyelitis.miR-182 and miR-10a are key regulators of Treg specialisation and stability during Schistosome and Leishmania-associated inflammation Induction of regulatory T cells by high-dose gp96 suppresses murine liver immune hyperactivation.Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function Retina-specific T regulatory cells bring about resolution and maintain remission of autoimmune uveitis.HY-Specific Induced Regulatory T Cells Display High Specificity and Efficacy in the Prevention of Acute Graft-versus-Host Disease Eos Is Redundant for Regulatory T Cell Function but Plays an Important Role in IL-2 and Th17 Production by CD4+ Conventional T Cells Regulatory T cell DNA methyltransferase inhibition accelerates resolution of lung inflammation.Relationship between regulatory T cells subsets and lipid profile in dyslipidemic patients: a longitudinal study during atorvastatin treatment Pim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal Phosphorylation Transcriptional regulatory networks for CD4 T cell differentiation.Treg cells, life history, and diversity Transcription factor Foxp3 and its protein partners form a complex regulatory network.Foxp3 expression is required for the induction of therapeutic tissue tolerance Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cells An obligate cell-intrinsic function for CD28 in Tregs Plasticity within the αβ⁺CD4⁺ T-cell lineage: when, how and what for?Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery.Generation and function of induced regulatory T cells.MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model.

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P2860

Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency.

http://www.wikidata.org/entity/Q35992006

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Loss of epigenetic modificatio ...... gulatory T cell insufficiency.

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Loss of epigenetic modificatio ...... gulatory T cell insufficiency.

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Loss of epigenetic modificatio ...... gulatory T cell insufficiency.

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Loss of epigenetic modificatio ...... gulatory T cell insufficiency.

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J.IMMUNI.2012.03.020

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Loss of epigenetic modificatio ...... gulatory T cell insufficiency.

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Bryan D Bell

http://www.w3.org/2001/XMLSchema#string

Dario A A Vignali

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David Finkelstein

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Drew M Pardoll

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Fan Pan

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Jerold E Rehg

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Jochen Huehn

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Matthew L Bettini

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Stefan Floess

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Steven F Ziegler

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P2860

FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

Tip60 is a co-repressor for STAT3

Where CD4+CD25+ T reg cells impinge on autoimmune diabetes

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation

How regulatory T cells work

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

Epigenetic control of the foxp3 locus in regulatory T cells

Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells

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