about
Selection of functional T cell receptor mutants from a yeast surface-display libraryHow (specific) would like your T-cells today? Generating T-cell therapeutic function through TCR-gene transferGrafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR.Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA.T cell receptor (TCR) gene therapy to treat melanoma: lessons from clinical and preclinical studies.Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins.HCV T Cell Receptor Chain Modifications to Enhance Expression, Pairing, and Antigen Recognition in T Cells for Adoptive Transfer.Regulation of T-cell antigen receptor (TCR) alpha-chain expression by TCR beta-chain transcripts.Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors.Targeting tumours with genetically enhanced T lymphocytes.Soluble T-cell receptors produced in human cells for targeted delivery.Therapeutic potential of a tumor-specific, MHC-unrestricted T-cell receptor expressed on effector cells of the innate and the adaptive immune system through bone marrow transduction and immune reconstitution.Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability.Stable, soluble, high-affinity, engineered T cell receptors: novel antibody-like proteins for specific targeting of peptide antigens.Covalent assembly of a soluble T cell receptor-peptide-major histocompatibility class I complex.Phage Display Engineered T Cell Receptors as Tools for the Study of Tumor Peptide-MHC Interactions.Transgenic TCR expression: comparison of single chain with full-length receptor constructs for T-cell function.Directed evolution of a stable scaffold for T-cell receptor engineering.Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system.
P2860
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P2860
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Functional three-domain single-chain T-cell receptors
@ast
Functional three-domain single-chain T-cell receptors
@en
type
label
Functional three-domain single-chain T-cell receptors
@ast
Functional three-domain single-chain T-cell receptors
@en
prefLabel
Functional three-domain single-chain T-cell receptors
@ast
Functional three-domain single-chain T-cell receptors
@en
P2093
P2860
P356
P1476
Functional three-domain single-chain T-cell receptors
@en
P2093
K W Wucherpfennig
S M Friedman
P2860
P304
12654-12658
P356
10.1073/PNAS.91.26.12654
P407
P577
1994-12-01T00:00:00Z