about
The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymeraseExtinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesisRibavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategiesArbovirus high fidelity variant loses fitness in mosquitoes and miceIMP dehydrogenase: structure, mechanism, and inhibition.Chikungunya Virus: In Vitro Response to Combination Therapy with Ribavirin and Interferon-α2aReporter-Expressing, Replicating-Competent Recombinant ArenavirusesJunín virus pathogenesis and virus replicationAnalysis of Ribavirin Mutagenicity in Human Hepatitis C Virus InfectionCounteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic TreatmentSequential structures provide insights into the fidelity of RNA replicationStructure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to RibavirinA Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-EscapePotential benefits of sequential inhibitor-mutagen treatments of RNA virus infectionsCell type mediated resistance of vesicular stomatitis virus and Sendai virus to ribavirinTargeting of arenavirus RNA synthesis by a carboxamide-derivatized aromatic disulfide with virucidal activityT-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitroCrimean-Congo hemorrhagic fever virus-encoded ovarian tumor protease activity is dispensable for virus RNA polymerase function.Targeting the proteolytic processing of the viral glycoprotein precursor is a promising novel antiviral strategy against arenaviruses.Inhibition of cellular entry of lymphocytic choriomeningitis virus by amphipathic DNA polymersComparison of the chronic effects of ribavirin and caffeic acid phenethyl ester (CAPE) on pancreatic damage and hepatotoxicity.Novel approaches in anti-arenaviral drug developmentRibavirin-induced anemia in hepatitis C virus patients undergoing combination therapy.Analysis of effect of antiviral therapy on regression of liver fibrosis in patient with HCV infectionUnderstanding the effect of the HCV polymerase inhibitor mericitabine on early viral kinetics in the phase 2 JUMP-C and PROPEL studies.Reverse genetics approaches to combat pathogenic arenavirusesINX-08189, a phosphoramidate prodrug of 6-O-methyl-2'-C-methyl guanosine, is a potent inhibitor of hepatitis C virus replication with excellent pharmacokinetic and pharmacodynamic properties.Biochemical impact of the host adaptation-associated PB2 E627K mutation on the temperature-dependent RNA synthesis kinetics of influenza A virus polymerase complexEmerging paramyxoviruses: molecular mechanisms and antiviral strategiesIdentification and Mechanism of Action of a Novel Small-Molecule Inhibitor of Arenavirus Multiplication.Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242.Role of the equilibrative and concentrative nucleoside transporters in the intestinal absorption of the nucleoside drug, ribavirin, in wild-type and Ent1(-/-) mice.Lassa Virus Cell Entry via Dystroglycan Involves an Unusual Pathway of Macropinocytosis.The role of the equilibrative nucleoside transporter 1 (ENT1) in transport and metabolism of ribavirin by human and wild-type or Ent1-/- mouse erythrocytes.The role of nucleoside transporters in the erythrocyte disposition and oral absorption of ribavirin in the wild-type and equilibrative nucleoside transporter 1-/- mice.Therapies for coronaviruses. Part 2: Inhibitors of intracellular life cycle.Reverse Genetics Approaches to Control Arenavirus.Current drug discovery strategies against arenavirus infections.Targeting the "cytokine storm" for therapeutic benefit.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Metabolism and antiviral activity of ribavirin.
@ast
Metabolism and antiviral activity of ribavirin.
@en
type
label
Metabolism and antiviral activity of ribavirin.
@ast
Metabolism and antiviral activity of ribavirin.
@en
prefLabel
Metabolism and antiviral activity of ribavirin.
@ast
Metabolism and antiviral activity of ribavirin.
@en
P1433
P1476
Metabolism and antiviral activity of ribavirin.
@en
P2093
William B Parker
P304
P356
10.1016/J.VIRUSRES.2004.11.006
P577
2005-02-01T00:00:00Z