Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells.
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Human 70-kDa SHP-1L differs from 68-kDa SHP-1 in its C-terminal structure and catalytic activityCD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1T cell recognition of weak ligands: roles of signaling, receptor number, and affinityRole of Tax protein in human T-cell leukemia virus type-I leukemogenicityJanus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Roles of TRAF3 in T cells: many surprisesStructure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognitionTumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell LeukemiaActivation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells.Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents.How to extinguish lymphocyte activation, immunotyrosine-based inhibition motif (ITIM)-bearing molecules a solution?Interleukin-2 signaling and inherited immunodeficiency.Notable roles of EZH2 and DNMT1 in epigenetic dormancy of the SHP1 gene during the progression of chronic myeloid leukaemia.HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes.Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy.The tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions.The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2.Janus kinases: components of multiple signaling pathways.Interferon-gamma is induced in human peripheral blood immune cells in vitro by sodium stibogluconate/interleukin-2 and mediates its antitumor activity in vivo.SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cellsIL-2-dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells.src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation.Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells.Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis.Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter.Negative regulation of the SH2-homology containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoproteinMultiple Pathways Control the Reactivation of Telomerase in HTLV-I-Associated Leukemia.Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses.Cellular level models as tools for cytokine design.Human T-cell lymphotropic virus type 1 p12I enhances interleukin-2 production during T-cell activation.Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia.Hematopoietic cytokine receptor signaling.Mechanisms of SHP-1 P2 promoter regulation in hematopoietic cells and its silencing in HTLV-1-transformed T cells.Novel role for interleukin-2 receptor-Jak signaling in retrovirus transmission.JAK2 inhibitors: what's the true therapeutic potential?Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity.Overview on HTLV-1 p12, p8, p30, p13: accomplices in persistent infection and viral pathogenesisSTAT3 activation: A key factor in tumor immunoescape.Human T-lymphotropic virus proteins and post-translational modification pathways
P2860
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P2860
Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Recruitment of SH2-containing ...... us type I-transformed T cells.
@ast
Recruitment of SH2-containing ...... us type I-transformed T cells.
@en
type
label
Recruitment of SH2-containing ...... us type I-transformed T cells.
@ast
Recruitment of SH2-containing ...... us type I-transformed T cells.
@en
prefLabel
Recruitment of SH2-containing ...... us type I-transformed T cells.
@ast
Recruitment of SH2-containing ...... us type I-transformed T cells.
@en
P2093
P2860
P356
P1476
Recruitment of SH2-containing ...... us type I-transformed T cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.7.3845
P407
P577
1998-03-01T00:00:00Z