Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling.
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Spliced leader RNA silencing (SLS) - a programmed cell death pathway in Trypanosoma brucei that is induced upon ER stressBAX activation is initiated at a novel interaction siteReevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na⁺/K⁺-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascadesConstitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cellsDifferential profile of Nix upregulation and translocation during hypoxia/ischaemia in vivo versus in vitroHistone deacetylase inhibitors strongly sensitise neuroblastoma cells to TRAIL-induced apoptosis by a caspases-dependent increase of the pro- to anti-apoptotic proteins ratio.Functional role of kallikrein 6 in regulating immune cell survival.Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cellsApoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality.A review of the mammalian unfolded protein response.A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growthCD4(+)CD25(+) regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis.Bim and Bmf in tissue homeostasis and malignant disease.Inhibition of Mcl-1 with the pan-Bcl-2 family inhibitor (-)BI97D6 overcomes ABT-737 resistance in acute myeloid leukemia.Pseudomonas aeruginosa ExoT Induces Mitochondrial Apoptosis in Target Host Cells in a Manner That Depends on Its GTPase-activating Protein (GAP) Domain Activity.BCL2 family of apoptosis-related genes: functions and clinical implications in cancer.A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosisBim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer.Garlic arrests MDA-MB-435 cancer cells in mitosis, phosphorylates the proapoptotic BH3-only protein BimEL and induces apoptosis.Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells.The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells.Loss of the BH3-only protein Bid does not rescue RelA-deficient embryos from TNF-R1-mediated fatal hepatocyte destruction.Caspases and kinases in a death grip.Bortezomib sensitizes human glioblastoma cells to induction of apoptosis by type I interferons through NOXA expression and Mcl-1 cleavageRituximab-induced early and late signaling have opposite effects on dexamethasone-induced apoptosis in human follicular lymphoma cells.Caspases and their substrates.MicroRNA-138 promotes acquired alkylator resistance in glioblastoma by targeting the Bcl-2-interacting mediator BIM.Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA.Synthetic human cell fate regulation by protein-driven RNA switches.The liver's dance with death: two Bcl-2 guardian proteins from the abyss.Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.Interactome Analysis of Microtubule-targeting Agents Reveals Cytotoxicity Bases in Normal Cells.Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity
P2860
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P2860
Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Caspase cleavage of BimEL trig ...... cation of apoptotic signaling.
@ast
Caspase cleavage of BimEL trig ...... cation of apoptotic signaling.
@en
type
label
Caspase cleavage of BimEL trig ...... cation of apoptotic signaling.
@ast
Caspase cleavage of BimEL trig ...... cation of apoptotic signaling.
@en
prefLabel
Caspase cleavage of BimEL trig ...... cation of apoptotic signaling.
@ast
Caspase cleavage of BimEL trig ...... cation of apoptotic signaling.
@en
P2860
P356
P1476
Caspase cleavage of BimEL trig ...... cation of apoptotic signaling.
@en
P2093
P2860
P304
P356
10.1073/PNAS.0308050100
P407
P577
2004-01-19T00:00:00Z