CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks.
about
CtIP is required to initiate replication-dependent interstrand crosslink repairCullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resectionDNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombinationCtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity.End resection at double-strand breaks: mechanism and regulation.The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination.Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cellsHomologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplicationOxidative stress diverts tRNA synthetase to nucleus for protection against DNA damageThe interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair.Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair.FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress.Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.Risky business: Microhomology-mediated end joining.Mechanism and regulation of DNA end resection in eukaryotesCtIP is required for DNA damage-dependent induction of P21.Structural studies of DNA end detection and resection in homologous recombination.Use of the HPRT gene to study nuclease-induced DNA double-strand break repair.Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resectionDevelopment of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells.Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms.SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.CtIP tetramer assembly is required for DNA-end resection and repair.When two is not enough: a CtIP tetramer is required for DNA repair by Homologous Recombination.BRCA2 antagonizes classical and alternative nonhomologous end-joining to prevent gross genomic instability.Meta-analysis of DNA double-strand break response kinetics.RBM45 competes with HDAC1 for binding to FUS in response to DNA damage.Pyruvate kinase M2 regulates homologous recombination-mediated DNA double-strand break repair
P2860
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P2860
CtIP protein dimerization is critical for its recruitment to chromosomal DNA double-stranded breaks.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
CtIP protein dimerization is c ...... al DNA double-stranded breaks.
@ast
CtIP protein dimerization is c ...... al DNA double-stranded breaks.
@en
type
label
CtIP protein dimerization is c ...... al DNA double-stranded breaks.
@ast
CtIP protein dimerization is c ...... al DNA double-stranded breaks.
@en
prefLabel
CtIP protein dimerization is c ...... al DNA double-stranded breaks.
@ast
CtIP protein dimerization is c ...... al DNA double-stranded breaks.
@en
P2093
P2860
P356
P1476
CtIP protein dimerization is c ...... al DNA double-stranded breaks.
@en
P2093
David J Chen
Hailong Wang
Lan N Truong
Linda Z Shi
Michael W Berns
Patty Yi-Hwa Hwang
Xiaohua Wu
Zhengping Shao
P2860
P304
21471-21480
P356
10.1074/JBC.M112.355354
P407
P577
2012-04-27T00:00:00Z