ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1. - Wikidata - awgldk - TriplyDB

ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1.

ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1.

http://www.wikidata.org/entity/Q36039129

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ENaC regulation by proteases and shear stress Pulmonary epithelial barrier function: some new players and mechanisms Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation Mutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors.Hypotonic shock modulates Na(+) current via a Cl(-) and Ca(2+)/calmodulin dependent mechanism in alveolar epithelial cells The membrane-anchored serine protease prostasin (CAP1/PRSS8) supports epidermal development and postnatal homeostasis independent of its enzymatic activity.Prostasin may contribute to chemoresistance, repress cancer cells in ovarian cancer, and is involved in the signaling pathways of CASP/PAK2-p34/actin.Matriptase zymogen supports epithelial development, homeostasis and regeneration Colon-specific deletion of epithelial sodium channel causes sodium loss and aldosterone resistance Membrane-anchored serine proteases in vertebrate cell and developmental biology The cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel.The channel-activating protease CAP1/Prss8 is required for placental labyrinth maturation.The epithelial sodium channel γ-subunit is processed proteolytically in human kidney.Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea.Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4.Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic Proteases PSP94, an upstream signaling mediator of prostasin found highly elevated in ovarian cancer.The serine protease prostasin (PRSS8) is a potential biomarker for early detection of ovarian cancer.A new look at electrolyte transport in the distal tubule Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells Cathepsin B is secreted apically from Xenopus 2F3 cells and cleaves the epithelial sodium channel (ENaC) to increase its activity.Phosphatidylinositol phosphate-dependent regulation of Xenopus ENaC by MARCKS protein.Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Membrane-anchored proteases in endothelial cell biology.A matriptase-prostasin reciprocal zymogen activation complex with unique features: prostasin as a non-enzymatic co-factor for matriptase activation.Membrane-anchored serine proteases in health and disease.Matriptase activation connects tissue factor-dependent coagulation initiation to epithelial proteolysis and signaling Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases.Mechanisms of renal NaCl retention in proteinuric disease.Urinary serine proteases and activation of ENaC in kidney--implications for physiological renal salt handling and hypertensive disorders with albuminuria.Relative roles of principal and intercalated cells in the regulation of sodium balance and blood pressure.The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.Delineation of proteolytic and non-proteolytic functions of the membrane-anchored serine protease prostasin.Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells.Severe Salt-Losing Syndrome and Hyperkalemia Induced by Adult Nephron-Specific Knockout of the Epithelial Sodium Channel α-Subunit.Amiloride-sensitive sodium channels and pulmonary edema.Listeriolysin O Causes ENaC Dysfunction in Human Airway Epithelial Cells.Alveolar nonselective channels are ASIC1a/α-ENaC channels and contribute to AFC.Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis.

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P2860

ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1.

http://www.wikidata.org/entity/Q36039129

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

@zh-sg

2010年學術文章

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2010年學術文章

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2010年學術文章

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name

ENaC-mediated alveolar fluid c ...... channel-activating protease 1.

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ENaC-mediated alveolar fluid c ...... channel-activating protease 1.

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type

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ENaC-mediated alveolar fluid c ...... channel-activating protease 1.

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ENaC-mediated alveolar fluid c ...... channel-activating protease 1.

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prefLabel

ENaC-mediated alveolar fluid c ...... channel-activating protease 1.

@ast

ENaC-mediated alveolar fluid c ...... channel-activating protease 1.

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EMBO Molecular Medicine

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ENaC-mediated alveolar fluid c ...... channel-activating protease 1.

@en

P2093

Bernard C Rossier

http://www.w3.org/2001/XMLSchema#string

Carole Planès

http://www.w3.org/2001/XMLSchema#string

Christine Clerici

http://www.w3.org/2001/XMLSchema#string

Edith Hummler

http://www.w3.org/2001/XMLSchema#string

Françoise Cluzeaud

http://www.w3.org/2001/XMLSchema#string

Grégoire Vuagniaux

http://www.w3.org/2001/XMLSchema#string

Nadia H Randrianarison

http://www.w3.org/2001/XMLSchema#string

Paul Soler

http://www.w3.org/2001/XMLSchema#string

Roch-Philippe Charles

http://www.w3.org/2001/XMLSchema#string

Simona Frateschi

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P2860

The epidermal barrier function is dependent on the serine protease CAP1/Prss8

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

Epithelial sodium channel related to proteins involved in neurodegeneration

Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry

Hypoxia and beta 2-agonists regulate cell surface expression of the epithelial sodium channel in native alveolar epithelial cells

Mouse prostasin gene structure, promoter analysis, and restricted expression in lung and kidney.

A segment of gamma ENaC mediates elastase activation of Na+ transport

Early restriction of peripheral and proximal cell lineages during formation of the lung.

Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats.

Functional ion channels in pulmonary alveolar type I cells support a role for type I cells in lung ion transport.

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26-37

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scholarly article

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10.1002/EMMM.200900050

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1

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2

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2010-01-01T00:00:00Z

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40820231

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20043279

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3377187

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