ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes. - Wikidata - awgldk - TriplyDB

ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.

ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.

http://www.wikidata.org/entity/Q36047531

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Different role of zinc transporter 8 between type 1 diabetes mellitus and type 2 diabetes mellitus Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets Current and Future Clinical Applications of Zinc Transporter-8 in Type 1 Diabetes Mellitus ZnT8-reactive T cells are weakly pathogenic in NOD mice but can participate in diabetes under inflammatory conditions Zinc transporter 8 and MAP3865c homologous epitopes are recognized at T1D onset in Sardinian children.Changes in Zinc Transporter 8 Autoantibodies Following Type 1 Diabetes Onset: The Type 1 Diabetes Genetics Consortium Autoantibody Workshop.Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1 Identification of Candidate Tolerogenic CD8(+) T Cell Epitopes for Therapy of Type 1 Diabetes in the NOD Mouse Model.Novel autoantigens in type 1 diabetes.Albuminuria according to status of autoimmunity and insulin sensitivity among youth with type 1 and type 2 diabetes CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.Zinc, pancreatic islet cell function and diabetes: new insights into an old story.Glucagon-reactive islet-infiltrating CD8 T cells in NOD mice.Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs.Anti-serum with anti-autoantibody activity decreases autoantibody-positive B lymphocytes and type 1 diabetes of female NOD mice.Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.Interferon-gamma ELISPOT detecting reactivity of T cells to TSH receptor peptides in Graves' disease.Comparison of autoantibody-positive and autoantibody-negative pediatric participants enrolled in the T1D Exchange clinic registry.T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes.Autoreactive T cells in type 1 diabetes.A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells.Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors.Zinc transporter 8 autoantibodies: what is their clinical relevance in gestational diabetes?Therapies to Suppress β Cell Autoimmunity in Type 1 Diabetes

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P2860

ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.

http://www.wikidata.org/entity/Q36047531

description

2012 nî lūn-bûn

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2012年論文

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2012年论文

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2012年论文

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ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.

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ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.

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ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.

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ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.

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ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.

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Bénédicte Michaud

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Christophe Marchi

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Emilie Barilleau

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Jean-Baptiste Arnoux

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Jean-Jacques Robert

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Roland Kratzer

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Yamina Hamel

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Émmanuelle Énée

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P2860

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

SYFPEITHI: database for MHC ligands and peptide motifs

Immunization of HLA class I transgenic mice identifies autoantigenic epitopes eliciting dominant responses in type 1 diabetes patients.

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.

Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8.

Contribution of antibodies against IA-2β and zinc transporter 8 to classification of diabetes diagnosed under 40 years of age.

Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus.

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells.

Histopathology of type 1 diabetes: old paradigms and new insights.

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes.

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1779-1784

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10.2337/DB12-0071

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7

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61

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Lucienne Chatenoud

Peter M van Endert

Jacques Beltrand

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2012-05-14T00:00:00Z

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224959180

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22586580

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type-1 diabetes

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