Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents.
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HDAC inhibitors as anti-inflammatory agentsReduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosisEpigenetic contributions in the development of rheumatoid arthritisHistone deacetylases as targets for treatment of multiple diseasesFOXP3: genetic and epigenetic implications for autoimmunityHistone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammationHistone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic childrenHistone deacetylase inhibition protects hearing against acute ototoxicity by activating the Nf-κB pathway.Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis.Histone deacetylase inhibitors: a chemical genetics approach to understanding cellular functions.Potent and orally efficacious bisthiazole-based histone deacetylase inhibitorsAntifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive ratsThe clinical development of histone deacetylase inhibitors as targeted anticancer drugs.Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia.Therapeutic effect of a novel histone deacetylase 6 inhibitor, CKD-L, on collagen-induced arthritis in vivo and regulatory T cells in rheumatoid arthritis in vitro.Vorinostat in advanced prostate cancer patients progressing on prior chemotherapy (National Cancer Institute Trial 6862): trial results and interleukin-6 analysis: a study by the Department of Defense Prostate Cancer Clinical Trial Consortium and UnSynthesis and biological evaluation of triazol-4-ylphenyl-bearing histone deacetylase inhibitors as anticancer agentsIncreased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritisHistone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs.Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.Histone deacetylases in skeletal development and bone mass maintenance.Muscle wasting associated with pathologic change is a risk factor for the exacerbation of joint swelling in collagen-induced arthritis in cynomolgus monkeysSuberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts.Imbalance between HAT and HDAC activities in the PBMCs of patients with ankylosing spondylitis or rheumatoid arthritis and influence of HDAC inhibitors on TNF alpha production.Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancerNatural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism.Hdac-mediated control of endochondral and intramembranous ossificationHistone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG miceProteases involved in cartilage matrix degradation in osteoarthritis.Inhibition of Histone Deacetylase Activity Aggravates Coxsackievirus B3-Induced Myocarditis by Promoting Viral Replication and Myocardial Apoptosis.Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?MicroRNA-222 regulates MMP-13 via targeting HDAC-4 during osteoarthritis pathogenesis.Rheumatoid arthritis and primary biliary cirrhosis: cause, consequence, or coincidence?HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy.Beyond receptors and signaling: epigenetic factors in the regulation of innate immunityThe histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation.HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in ratsTargeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?A novel domain in histone deacetylase 1 and 2 mediates repression of cartilage-specific genes in human chondrocytesA novel histone deacetylase inhibitor prevents IL-1beta induced metabolic dysfunction in pancreatic beta-cells.
P2860
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P2860
Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Anti-rheumatic activities of h ...... -induced arthritis in rodents.
@ast
Anti-rheumatic activities of h ...... -induced arthritis in rodents.
@en
type
label
Anti-rheumatic activities of h ...... -induced arthritis in rodents.
@ast
Anti-rheumatic activities of h ...... -induced arthritis in rodents.
@en
prefLabel
Anti-rheumatic activities of h ...... -induced arthritis in rodents.
@ast
Anti-rheumatic activities of h ...... -induced arthritis in rodents.
@en
P2093
P2860
P356
P1476
Anti-rheumatic activities of h ...... n-induced arthritis in rodents
@en
P2093
E Bastianelli
L Lepescheux
P Clément-Lacroix
P2860
P304
P356
10.1038/SJ.BJP.0707165
P407
P577
2007-02-26T00:00:00Z