Combined hERG channel inhibition and disruption of trafficking in drug-induced long QT syndrome by fluoxetine: a case-study in cardiac safety pharmacology.
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Computational methods in drug discoveryThe Role of Interaction Model in Simulation of Drug Interactions and QT ProlongationADMET evaluation in drug discovery. 12. Development of binary classification models for prediction of hERG potassium channel blockagehERG-related drug toxicity and models for predicting hERG liability and QT prolongation.Selective serotonin reuptake inhibitors and torsade de pointes: new concepts and new directions derived from a systematic review of case reportsSudden death in patients receiving drugs tending to prolong the QT interval.hERG subunit composition determines differential drug sensitivity.Drugs and trafficking of ion channels: a new pro-arrhythmic threat on the horizon?Lack of electrocardiographic effect of dexlansoprazole MR, a novel modified-release formulation of the proton pump inhibitor dexlansoprazole, in healthy participants.
P2860
Q26997089-9B0F69A6-2732-4297-8559-024CA192A8A0Q28077218-83593970-0BA0-44EC-88C3-2D4BCC60C4ECQ28730653-D0E308B0-A822-4027-81FC-2A90CB3D8D2EQ33845924-1607059A-2E61-41F1-BA78-97C2D055516FQ34016220-2DECB3E7-5A54-485D-99F7-150D5B44B4B0Q37471104-F311FD0E-7C7F-4A92-A96F-C44B4A172524Q38649960-F3D9328C-0C71-44FB-9029-36B7FD51F398Q41856022-13FDDE60-9B2D-4949-8B79-B3DBB8B27C26Q43262191-06FC4D43-41A7-4D47-BB72-2F110833ABFA
P2860
Combined hERG channel inhibition and disruption of trafficking in drug-induced long QT syndrome by fluoxetine: a case-study in cardiac safety pharmacology.
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2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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name
Combined hERG channel inhibiti ...... n cardiac safety pharmacology.
@ast
Combined hERG channel inhibiti ...... n cardiac safety pharmacology.
@en
type
label
Combined hERG channel inhibiti ...... n cardiac safety pharmacology.
@ast
Combined hERG channel inhibiti ...... n cardiac safety pharmacology.
@en
prefLabel
Combined hERG channel inhibiti ...... n cardiac safety pharmacology.
@ast
Combined hERG channel inhibiti ...... n cardiac safety pharmacology.
@en
P2860
P356
P1476
Combined hERG channel inhibiti ...... in cardiac safety pharmacology
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P2093
J C Hancox
P2860
P304
P356
10.1038/SJ.BJP.0706890
P407
P577
2006-09-11T00:00:00Z