ERAP1 functions override the intrinsic selection of specific antigens as immunodominant peptides, thereby altering the potency of antigen-specific cytolytic and effector memory T-cell responses
about
A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition.Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2Long-term, high-level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus.Mice expressing human ERAP1 variants associated with ankylosing spondylitis have altered T-cell repertoires and NK cell functions, as well as increased in utero and perinatal mortality.ERAP1/ERAP2 and RUNX3 polymorphisms are not associated with ankylosing spondylitis susceptibility in Chinese Han.ERAP1 deficient mice have reduced Type 1 regulatory T cells and develop skeletal and intestinal features of Ankylosing Spondylitis
P2860
ERAP1 functions override the intrinsic selection of specific antigens as immunodominant peptides, thereby altering the potency of antigen-specific cytolytic and effector memory T-cell responses
description
2014 nî lūn-bûn
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2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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2014年论文
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2014年论文
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name
ERAP1 functions override the i ...... fector memory T-cell responses
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ERAP1 functions override the i ...... fector memory T-cell responses
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type
label
ERAP1 functions override the i ...... fector memory T-cell responses
@ast
ERAP1 functions override the i ...... fector memory T-cell responses
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prefLabel
ERAP1 functions override the i ...... fector memory T-cell responses
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ERAP1 functions override the i ...... fector memory T-cell responses
@en
P2093
P2860
P356
P1476
ERAP1 functions override the i ...... fector memory T-cell responses
@en
P2093
Andrea Amalfitano
David P W Rastall
Sarah Godbehere
Sergey S Seregin
Yasser A Aldhamen
P2860
P304
P356
10.1093/INTIMM/DXU078
P577
2014-08-02T00:00:00Z