Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders. - Wikidata - awgldk - TriplyDB

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

http://www.wikidata.org/entity/Q36079508

about

Notch-Mediated Cell Adhesion Impact of notch signaling on inflammatory responses in cardiovascular disorders Notch signaling as a novel regulator of metabolism The role of notch in the cardiovascular system: potential adverse effects of investigational notch inhibitors PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation Adipocyte-specific blockade of gamma-secretase, but not inhibition of Notch activity, reduces adipose insulin sensitivity.Decline of FOXN1 gene expression in human thymus correlates with age: possible epigenetic regulation.The macrophage A2B adenosine receptor regulates tissue insulin sensitivity Fatty acid-binding protein 4, a point of convergence for angiogenic and metabolic signaling pathways in endothelial cells.Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity Adipose tissue remodeling in a novel domestic porcine model of diet-induced obesity.An evolutionary-conserved function of mammalian notch family members as cell adhesion molecules Expanding role of delta-like 4 mediated notch signaling in cardiovascular and metabolic diseases Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice.Increased Vascularization in the Vulnerable Upstream Regions of Both Early and Advanced Human Carotid Atherosclerosis.Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis.Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance CD163 interacts with TWEAK to regulate tissue regeneration after ischaemic injury Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression.Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.Gamma-secretase Inhibitor Prevents Proliferation and Migration of Ductus Arteriosus Smooth Muscle Cells through the Notch3-HES1/2/5 Pathway Macrophage Notch Ligand Delta-Like 4 Promotes Vein Graft Lesion Development: Implications for the Treatment of Vein Graft Failure.Analysis of gene expression profile identifies potential biomarkers for atherosclerosis.Hepatic notch signaling correlates with insulin resistance and nonalcoholic fatty liver disease.Adipose tissue angiogenesis: impact on obesity and type-2 diabetes.Notch, lipids, and endothelial cells.Molecular biology of atherosclerosis.The role of Notch pathway in cardiovascular diseases.Notch signaling in blood vessels: from morphogenesis to homeostasis.Notch signal integration in the vasculature during remodeling Macrophages in Vascular Inflammation: Origins and Functions.Delta-Like Ligand 4-Notch Signaling in Macrophage Activation.Notch signaling in cerebrovascular diseases (Review)Primary human monocytes differentiate into M2 macrophages and involve Notch-1 pathway.Inflammation and Notch signaling: a crosstalk with opposite effects on tumorigenesis Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability.DLL4/Notch1 and BMP9 Interdependent Signaling Induces Human Endothelial Cell Quiescence via P27KIP1 and Thrombospondin-1.Current Challenges in Translating Tissue-Engineered Heart Valves.Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot study Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia.

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P2860

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

http://www.wikidata.org/entity/Q36079508

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

@ast

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

@en

type

label

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

@ast

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

@en

prefLabel

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

@ast

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

@en

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PNAS.1116889109

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders.

@en

P2093

Aleksey Chudnovskiy

http://www.w3.org/2001/XMLSchema#string

Cem Z Gorgun

http://www.w3.org/2001/XMLSchema#string

Daiju Fukuda

http://www.w3.org/2001/XMLSchema#string

Elena Aikawa

http://www.w3.org/2001/XMLSchema#string

Gökhan S Hotamisligil

http://www.w3.org/2001/XMLSchema#string

Hideo Yagita

http://www.w3.org/2001/XMLSchema#string

Hiroyuki Yamazaki

http://www.w3.org/2001/XMLSchema#string

Jon C Aster

http://www.w3.org/2001/XMLSchema#string

Kevin Croce

http://www.w3.org/2001/XMLSchema#string

Masanori Aikawa

http://www.w3.org/2001/XMLSchema#string

P2860

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

Exploring the full spectrum of macrophage activation

Inflammation and metabolic disorders

Obesity is associated with macrophage accumulation in adipose tissue

Notch signaling: cell fate control and signal integration in development

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes

Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

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E1868-77

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scholarly article

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10.1073/PNAS.1116889109

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P433

27

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109

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Filip K Swirski

Ralph Weissleder

P577

2012-06-13T00:00:00Z

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225374367

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P698

22699504

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P921

atherosclerosis

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3390871

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