Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
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Notch-Mediated Cell AdhesionNotch signaling as a novel regulator of metabolismFringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligandsNotch ligand delta-like1: X-ray crystal structure and binding affinityContext-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In VivoStructure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutations.Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning.Selective regulation of Notch ligands during angiogenesis is mediated by vimentinCytokine (IL16) and tyrphostin actions on ovarian primordial follicle development.Proteomic analysis reveals CACN-1 is a component of the spliceosome in Caenorhabditis elegans.Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states.Structural biology. Structural basis for Notch1 engagement of Delta-like 4Blockade of specific NOTCH ligands: a new promising approach in cancer therapyNotch1 is pan-endothelial at the onset of flow and regulated by flow.Frequency and distribution of Notch mutations in tumor cell lines.Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory RegionContext-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.Therapeutic modulation of Notch signalling--are we there yet?Significance of glycosylation in Notch signaling.The multiple roles of epidermal growth factor repeat O-glycans in animal development.Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1.Notch signaling in lung diseases: focus on Notch1 and Notch3.The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands.The Varied Roles of Notch in Cancer.Identification and characterization of a novel Sso7d scaffold-based binder against Notch1.Refining a Jagged edge.Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.Identification of Domains for Efficient Notch Signaling Activity in Immobilized Notch Ligand Proteins.Inhibition of Delta-induced Notch signaling using fucose analogs.Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development.Structural Basis for Regulated Proteolysis by the α-Secretase ADAM10.Therapeutic effects of histone deacetylase inhibitors on kidney disease.Signal Transduction: Notch catches a Jagged edge.
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P2860
Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 July 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
@en
Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
@nl
type
label
Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
@en
Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
@nl
prefLabel
Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
@en
Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
@nl
P2093
P2860
P356
P1476
Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.
@en
P2093
Jarrod A Marto
Jon C Aster
Marie Blanke Andrawes
Scott B Ficarro
Stephen C Blacklow
P2860
P304
25477-25489
P356
10.1074/JBC.M113.454850
P407
P577
2013-07-09T00:00:00Z