TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells. - Wikidata - awgldk - TriplyDB

TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

http://www.wikidata.org/entity/Q36088939

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Impact of Inflammation on Myeloproliferative Neoplasm Symptom Development The inherited bone marrow failure syndromes Fanconi anemia and the cell cycle: new perspectives on aneuploidy Mouse models of Fanconi anemia Evolved tumor suppression: why are we so good at not getting cancer?H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling.Fanconi anemia proteins and their interacting partners: a molecular puzzle Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML.An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.TNF-α promotes gallbladder cancer cell growth and invasion through autocrine mechanisms Diamond-Blackfan anemia: diagnosis, treatment, and molecular pathogenesis.Direct inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2.Differential behaviour of normal, transformed and Fanconi's anemia lymphoblastoid cells to modeled microgravity.p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes Spontaneous abrogation of the G₂DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients.Concise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cells Bone marrow cell transcripts from Fanconi anaemia patients reveal in vivo alterations in mitochondrial, redox and DNA repair pathways.Inactivation of a common OGG1 variant by TNF-alpha in mammalian cells.TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms.Chromosomal aberrations associated with clonal evolution and leukemic transformation in fanconi anemia: clinical and biological implications.Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies.Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.FANCL ubiquitinates β-catenin and enhances its nuclear function.Fanconi anemia links reactive oxygen species to insulin resistance and obesity.The Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma.TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice.TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia.TNF-α, a good or bad factor in hematological diseases?The PI3K/Akt1 pathway enhances steady-state levels of FANCL.Distinct roles of stress-activated protein kinases in Fanconi anemia-type C-deficient hematopoiesis.Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells.Oxidative stress in Fanconi anemia hematopoiesis and disease progression.Myelodysplasia and acute leukemia as late complications of marrow failure: future prospects for leukemia prevention.The Fanconi anemia/BRCA gene network in zebrafish: embryonic expression and comparative genomics.FANCA and FANCC modulate TLR and p38 MAPK-dependent expression of IL-1β in macrophages.Shwachman-Diamond syndrome: implications for understanding the molecular basis of leukaemia.TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells.Finding the needle in the hay stack: hematopoietic stem cells in Fanconi anemia.Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity.Maintenance of genome stability by Fanconi anemia proteins.

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TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

http://www.wikidata.org/entity/Q36088939

description

2007 nî lūn-bûn

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2007年論文

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name

TNF-alpha induces leukemic clo ...... mia group C murine stem cells.

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TNF-alpha induces leukemic clo ...... mia group C murine stem cells.

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TNF-alpha induces leukemic clo ...... mia group C murine stem cells.

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TNF-alpha induces leukemic clo ...... mia group C murine stem cells.

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TNF-alpha induces leukemic clo ...... mia group C murine stem cells.

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TNF-alpha induces leukemic clo ...... mia group C murine stem cells.

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Journal of Clinical Investigation

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TNF-alpha induces leukemic clo ...... emia group C murine stem cells

@en

P2093

Daniel P Sejas

http://www.w3.org/2001/XMLSchema#string

David A Williams

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Hartmut Geiger

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June Li

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Kalpana J Nattamai

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Keaney R Rathbun

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Qishen Pang

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Reena Rani

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Xiaoling Zhang

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Yuhui Qiu

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P2860

The Fanconi anaemia group G gene FANCG is identical with XRCC9

Isolation of a cDNA representing the Fanconi anemia complementation group E gene

The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity.

The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors

Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

Fanconi anaemia

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

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3283-3295

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10.1172/JCI31772

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11

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117

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2007-11-01T00:00:00Z

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17960249

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