Linking double-stranded DNA breaks to the recombination activating gene complex directs repair to the nonhomologous end-joining pathway
about
Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaksRole of non-homologous end joining in V(D)J recombinationThe in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci.Choosing the right path: does DNA-PK help make the decision?Inhibition of homologous recombination by DNA-dependent protein kinase requires kinase activity, is titratable, and is modulated by autophosphorylation.RAG1-mediated ubiquitylation of histone H3 is required for chromosomal V(D)J recombination.A dual interaction between the DNA damage response protein MDC1 and the RAG1 subunit of the V(D)J recombinaseRedundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination.Evidence for Ku70/Ku80 association with full-length RAG1.Restoration of ATM Expression in DNA-PKcs-Deficient Cells Inhibits Signal End Joining.DNA repair in murine embryonic stem cells and differentiated cellsHuman induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining.The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers.Mechanisms maintaining genomic integrity in embryonic stem cells and induced pluripotent stem cellsNew insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination.Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV-deficient B cells.iRAGu: A Novel Inducible and Reversible Mouse Model for Ubiquitous Recombinase Activity.Epigenetic modifications of the VH region after DJH recombination in Pro-B cells.
P2860
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P2860
Linking double-stranded DNA breaks to the recombination activating gene complex directs repair to the nonhomologous end-joining pathway
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Linking double-stranded DNA br ...... homologous end-joining pathway
@ast
Linking double-stranded DNA br ...... homologous end-joining pathway
@en
type
label
Linking double-stranded DNA br ...... homologous end-joining pathway
@ast
Linking double-stranded DNA br ...... homologous end-joining pathway
@en
prefLabel
Linking double-stranded DNA br ...... homologous end-joining pathway
@ast
Linking double-stranded DNA br ...... homologous end-joining pathway
@en
P2860
P356
P1476
Linking double-stranded DNA br ...... homologous end-joining pathway
@en
P2093
Katheryn Meek
Xiaoping Cui
P2860
P304
17046-17051
P356
10.1073/PNAS.0610928104
P407
P577
2007-10-15T00:00:00Z