Choosing the right path: does DNA-PK help make the decision? - Wikidata - awgldk - TriplyDB

Choosing the right path: does DNA-PK help make the decision?

Choosing the right path: does DNA-PK help make the decision?

http://www.wikidata.org/entity/Q35029335

about

DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3 Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)XRCC4's interaction with XLF is required for coding (but not signal) end joining DNA damage and repair in plants - from models to crops Beyond DNA repair: DNA-PK function in cancer SIRT1 as a therapeutic target in inflammaging of the pulmonary disease DNA DSB repair pathway choice: an orchestrated handover mechanism Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation.The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis Preventing Damage Limitation: Targeting DNA-PKcs and DNA Double-Strand Break Repair Pathways for Ovarian Cancer Therapy Mutations in the NHEJ component XRCC4 cause primordial dwarfism ATM, ATR and DNA-PKcs expressions correlate to adverse clinical outcomes in epithelial ovarian cancers Types, causes, detection and repair of DNA fragmentation in animal and human sperm cells Mechanisms for Structural Variation in the Human Genome Non-homologous end joining: emerging themes and unanswered questions.Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time Two cellular protein kinases, DNA-PK and PKA, phosphorylate the adenoviral L4-33K protein and have opposite effects on L1 alternative RNA splicing Role of AKT signaling in DNA repair and clinical response to cancer therapy.Minichromosome maintenance 2 bound with retroviral Gp70 is localized to cytoplasm and enhances DNA-damage-induced apoptosis.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.Utility of a histone deacetylase inhibitor (PXD101) for thyroid cancer treatment.Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.SV40 utilizes ATM kinase activity to prevent non-homologous end joining of broken viral DNA replication products Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks.Complex cisplatin-double strand break (DSB) lesions directly impair cellular non-homologous end-joining (NHEJ) independent of downstream damage response (DDR) pathways Smad4 loss promotes lung cancer formation but increases sensitivity to DNA topoisomerase inhibitors.A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines.Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells.DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.Transcriptional modulation induced by ionizing radiation: p53 remains a central player.DNA-dependent protein kinase and its inhibition in support of radiotherapy.Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining.Repair of double-strand breaks by end joining.The biogenesis of chromosome translocations.HSV-I and the cellular DNA damage response.Molecular mechanisms involved in initiation of the DNA damage response.PRKDC mutations in a SCID patient with profound neurological abnormalities.Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers.Small Molecules, Inhibitors of DNA-PK, Targeting DNA Repair, and Beyond.Unraveling the complexities of DNA-dependent protein kinase autophosphorylation.

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Choosing the right path: does DNA-PK help make the decision?

http://www.wikidata.org/entity/Q35029335

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

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name

Choosing the right path: does DNA-PK help make the decision?

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Choosing the right path: does DNA-PK help make the decision?

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Choosing the right path: does DNA-PK help make the decision?

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Choosing the right path: does DNA-PK help make the decision?

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Choosing the right path: does DNA-PK help make the decision?

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J.MRFMMM.2011.02.010

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Mutation Research

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Choosing the right path: does DNA-PK help make the decision?

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Jessica A Neal

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Katheryn Meek

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P2860

Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

Crystal structure of an Xrcc4-DNA ligase IV complex

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

Phosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinase

Purified human BRCA2 stimulates RAD51-mediated recombination

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73-86

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scholarly article

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10.1016/J.MRFMMM.2011.02.010

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1-2

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711

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2011-03-03T00:00:00Z

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50287940

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21376743

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3109507

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