Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
about
Anti-Cancer Stem-like Cell Compounds in Clinical Development - An Overview and Critical AppraisalCellular and molecular biology of small cell lung cancer: an overviewNotch-Mediated Cell AdhesionContext-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In VivoRegulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase RumiPtf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanismO-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand functionO-fucosylation of DLL3 is required for its function during somitogenesisNotch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actinThe intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activityAcheate-scute like 1 (Ascl1) is required for normal delta-like (Dll) gene expression and notch signaling during retinal developmentDynamic interactions between intermediate neurogenic progenitors and radial glia in embryonic mouse neocortex: potential role in Dll1-Notch signalingThe canonical Notch signaling pathway: unfolding the activation mechanism.The atypical mammalian ligand Delta-like homologue 1 (Dlk1) can regulate Notch signalling in DrosophilaNotch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.Morphogen pathways as molecular targets for the treatment of fibrosis in systemic sclerosis.A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivoDiscrete Notch signaling requirements in the specification of hematopoietic stem cells.Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the diseaseAn evolutionary-conserved function of mammalian notch family members as cell adhesion moleculesGeneration of an 870 kb deletion encompassing the Skt/Etl4 locus by combination of inter- and intra-chromosomal recombinationSpatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone.Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.The many facets of Notch ligands.The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling.Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates.EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development.Canonical and non-canonical Notch ligands.Bidirectional transport between the trans-Golgi network and the endosomal system.The mouse notches up another success: understanding the causes of human vertebral malformation.Differential requirements for Wnt and Notch signaling in hematopoietic versus thymic niches.Ubiquitinations in the notch signaling pathway.Distinct contextual roles for Notch signalling in skeletal muscle stem cellsTherapeutic modulation of Notch signalling--are we there yet?Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligandsDelta-like 3 is silenced by methylation and induces apoptosis in human hepatocellular carcinoma.Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer.
P2860
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P2860
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
@ast
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
@en
type
label
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
@ast
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
@en
prefLabel
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
@ast
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
@en
P2093
P2860
P356
P1476
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
@en
P2093
Achim Gossler
Duncan B Sparrow
Elisabeth Kremmer
Gavin Chapman
Insa Geffers
Karin Schuster-Gossler
Katrin Serth
Ralf Cordes
Robert Jaekel
Sally L Dunwoodie
P2860
P304
P356
10.1083/JCB.200702009
P407
P577
2007-07-01T00:00:00Z