Cyclooxygenase-dependent lipid-modification of brain proteins.
about
Treatment with a γ-ketoaldehyde scavenger prevents working memory deficits in hApoE4 mice.Characterization of scavengers of gamma-ketoaldehydes that do not inhibit prostaglandin biosynthesis.Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1.Determination of 3-methoxysalicylamine levels in mouse plasma and tissue by liquid chromatography-tandem mass spectrometry: application to in vivo pharmacokinetics studiesReactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells.PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice.Levuglandin forms adducts with histone h4 in a cyclooxygenase-2-dependent manner, altering its interaction with DNA.Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and diagnostic target in neurodegeneration, neurotrauma and neuro-injuries.Molecular Structures of Isolevuglandin-Protein Cross-Links.Amyloid Plaque-Associated Oxidative Degradation of Uniformly Radiolabeled Arachidonic Acid.Total Synthesis Confirms the Molecular Structure Proposed for Oxidized Levuglandin D2.
P2860
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P2860
Cyclooxygenase-dependent lipid-modification of brain proteins.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Cyclooxygenase-dependent lipid-modification of brain proteins.
@ast
Cyclooxygenase-dependent lipid-modification of brain proteins.
@en
type
label
Cyclooxygenase-dependent lipid-modification of brain proteins.
@ast
Cyclooxygenase-dependent lipid-modification of brain proteins.
@en
prefLabel
Cyclooxygenase-dependent lipid-modification of brain proteins.
@ast
Cyclooxygenase-dependent lipid-modification of brain proteins.
@en
P2093
P1433
P1476
Cyclooxygenase-dependent lipid-modification of brain proteins.
@en
P2093
Irène Zagol-Ikapitte
John A Oates
Katrin I Andreasson
Olivier Boutaud
P304
P356
10.1111/J.1750-3639.2005.TB00510.X
P577
2005-04-01T00:00:00Z