N4-phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease
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The pilot phase of the NIH Chemical Genomics Center.NIMH initiatives to facilitate collaborations among industry, academia, and government for the discovery and clinical testing of novel models and drugs for psychiatric disordersDiscovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidaseGlycosphingolipids--nature, function, and pharmacological modulation.Design and Synthesis of Potent Quinazolines as Selective β-Glucocerebrosidase ModulatorsAn efficient chemical approach to bispecific antibodies and antibodies of high valencyAmbroxol as a pharmacological chaperone for mutant glucocerebrosidase.β-Glucocerebrosidase Modulators Promote Dimerization of β-Glucocerebrosidase and Reveal an Allosteric Binding Site.
P2860
Q33508908-C65D6B40-5482-4677-BBB7-FE1D52EE9B88Q34050607-60996D1A-ADC2-4498-B479-6AD1FAAF4FDEQ34286005-47061F9E-E5C9-4358-A1A2-330E086D0610Q37622816-26EB584D-6534-4D78-BF6D-7C786E82967BQ38824056-4093AD32-7C6B-4EE9-8B69-3882F0831A90Q39842559-98EED431-EB6C-42EE-AE09-73B1F5960D46Q42763507-0FA84C5F-6FE1-4B86-B9E0-C174F853FF46Q52574646-A6DEE822-D6FE-40D5-9FEB-FFC5CAE7DECC
P2860
N4-phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
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2007年论文
@zh-cn
name
N4-phenyl modifications of N2- ...... chaperones for Gaucher disease
@ast
N4-phenyl modifications of N2- ...... chaperones for Gaucher disease
@en
type
label
N4-phenyl modifications of N2- ...... chaperones for Gaucher disease
@ast
N4-phenyl modifications of N2- ...... chaperones for Gaucher disease
@en
prefLabel
N4-phenyl modifications of N2- ...... chaperones for Gaucher disease
@ast
N4-phenyl modifications of N2- ...... chaperones for Gaucher disease
@en
P2093
P2860
P1476
N4-phenyl modifications of N2- ...... chaperones for Gaucher disease
@en
P2093
Craig J Thomas
Daniel J Urban
Ellen Sidransky
James Inglese
Wenwei Huang
P2860
P304
P356
10.1016/J.BMCL.2007.08.050
P407
P577
2007-08-28T00:00:00Z