Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen.
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Alpha 1 beta 1 integrin heterodimer functions as a dual laminin/collagen receptor in neural cellsInteraction of type IV collagen with the isolated integrins alpha 1 beta 1 and alpha 2 beta 1Function and spatial distribution in developing chick retina of the laminin receptor alpha 6 beta 1 and its isoformsCharacterization of the integrin alpha 8 subunit: a new integrin beta 1-associated subunit, which is prominently expressed on axons and on cells in contact with basal laminae in chick embryosRanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1.Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity.Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivoThe human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others.Integrin alpha 8 beta 1 promotes attachment, cell spreading, and neurite outgrowth on fibronectinExpression of VLA-alpha 2, VLA-alpha 6, and VLA-beta 1 chains in normal mucosa and adenomas of the colon, and in colon carcinomas and their liver metastases.Integrin heterodimer and receptor complexity in avian and mammalian cells.Laminin induces the stable expression of surface galactosyltransferase on lamellipodia of migrating cellsAnalysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organizationSignal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor.Adhesomes: specific granules containing receptors for laminin, C3bi/fibrinogen, fibronectin, and vitronectin in human polymorphonuclear leukocytes and monocytesHepatocyte attachment to laminin is mediated through multiple receptors.Cell surface galactosyltransferase mediates the initiation of neurite outgrowth from PC12 cells on lamininSpatiotemporal segregation of endothelial cell integrin and nonintegrin extracellular matrix-binding proteins during adhesion events.The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin.Characterization of a synthetic peptide from type IV collagen that promotes melanoma cell adhesion, spreading, and motilityRecognition of the laminin E8 cell-binding site by an integrin possessing the alpha 6 subunit is essential for epithelial polarization in developing kidney tubules.Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex.The NC1 domain of type IV collagen promotes axonal growth in sympathetic neurons through interaction with the alpha 1 beta 1 integrin.Laminin receptors in the retina: sequence analysis of the chick integrin alpha 6 subunit. Evidence for transcriptional and posttranslational regulation.Laminin fragment E8 mediates PC12 cell neurite outgrowth by binding to cell surface beta 1,4 galactosyltransferase.Adhesion of a chicken myeloblast cell line to fibrinogen and vitronectin through a beta 1-class integrin.Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the beta 1 integrin subunitGlial cells in development. In vivo and in vitro approaches.Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts.Extracellular matrix molecules and their receptors: functions in neural development.Chick integrin alpha V subunit molecular analysis reveals high conservation of structural domains and association with multiple beta subunits in embryo fibroblasts.Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene.Laminin in neuronal development.A cell-free system to study regulation of focal adhesions and of the connected actin cytoskeleton.Real-time monitoring of extracellular matrix-mediated PC12 cell attachment and proliferation using an electronic biosensing device.Vaccinia virus induces Ca2+-independent cell-matrix adhesion during the motile phase of infectionAdhesion molecules and their role in cancer metastasis.The alpha 1 beta 1 integrin recognition site of the basement membrane collagen molecule [alpha 1(IV)]2 alpha 2(IV).Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice.
P2860
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P2860
Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Purification and characterizat ...... laminin and type IV collagen.
@ast
Purification and characterizat ...... laminin and type IV collagen.
@en
type
label
Purification and characterizat ...... laminin and type IV collagen.
@ast
Purification and characterizat ...... laminin and type IV collagen.
@en
prefLabel
Purification and characterizat ...... laminin and type IV collagen.
@ast
Purification and characterizat ...... laminin and type IV collagen.
@en
P2093
P2860
P356
P1476
Purification and characterizat ...... laminin and type IV collagen.
@en
P2093
C H Damsky
K J Tomaselli
L F Reichardt
P2860
P304
P356
10.1083/JCB.107.3.1241
P407
P577
1988-09-01T00:00:00Z