Transformation of NIH 3T3 cells with basic fibroblast growth factor or the hst/K-fgf oncogene causes downregulation of the fibroblast growth factor receptor: reversal of morphological transformation and restoration of receptor number by suramin.
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Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factorsSuramin rapidly alters cellular tyrosine phosphorylation in prostate cancer cell lines.Differential fibroblast growth factor 8 (FGF8)-mediated autoregulation of its cognate receptors, Fgfr1 and Fgfr3, in neuronal cell linesAutocrine transformation by chimeric signal peptide-basic fibroblast growth factor: reversal by suramin.Fgf-9 is required for angiogenesis and osteogenesis in long bone repair.Angiotensin II induces delayed mitogenesis and cellular proliferation in rat aortic smooth muscle cells. Correlation with the expression of specific endogenous growth factors and reversal by suramin.Preparation of Proper Immunogen by Cloning and Stable Expression of cDNA coding for Human Hematopoietic Stem Cell Marker CD34 in NIH-3T3 Mouse Fibroblast Cell LineSuramin and radiotherapy in newly diagnosed glioblastoma: phase 2 NABTT CNS Consortium study.Cloning and Stable Expression of cDNA Coding For Platelet Endothelial Cell Adhesion Molecule -1 (PECAM-1, CD31) in NIH-3T3 Cell Line.Suramin inhibits bFGF-induced endothelial cell proliferation and angiogenesis in the chick chorioallantoic membrane.A structure-activity analysis of antagonism of the growth factor and angiogenic activity of basic fibroblast growth factor by suramin and related polyanionsDifferential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms.Adeno-associated viral vectors based on serotype 3b use components of the fibroblast growth factor receptor signaling complex for efficient transductionThe K-fgf/hst oncogene induces transformation through an autocrine mechanism that requires extracellular stimulation of the mitogenic pathwayHerpes simplex virus infection can occur without involvement of the fibroblast growth factor receptorSelective expression of high molecular weight basic fibroblast growth factor confers a unique phenotype to NIH 3T3 cells.Modulation of fibroblast growth factor-2 receptor binding, dimerization, signaling, and angiogenic activity by a synthetic heparin-mimicking polyanionic compound.Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine mannerInvolvement of basic fibroblast growth factor in suramin-induced inhibition of V79/AP4 fibroblast cell proliferation.Differential regulation of fibroblast growth factor (FGF) receptor-1 mRNA and protein by two molecular forms of basic FGF. Modulation of FGFR-1 mRNA stability.The expression and localization of urokinase-type plasminogen activator and its type 1 inhibitor are regulated by retinoic acid and fibroblast growth factor in human teratocarcinoma cells.Basic fibroblast growth factor requires a long-lasting activation of protein kinase C to induce cell proliferation in transformed fetal bovine aortic endothelial cells.Paracrine and autocrine effects of fibroblast growth factor-4 in endothelial cells.Noncompetitive, chemokine-mediated inhibition of basic fibroblast growth factor-induced endothelial cell proliferation.A transformed neonatal rat retinal pigment epithelial cell line: secreted protein analysis and fibroblast growth factor and receptor expression.Tumoral progression of human breast epithelial cells secreting FGF2 and FGF4.Cooperative roles of hepatocyte growth factor and plasminogen activator in tubular morphogenesis by human microvascular endothelial cells.Glypican-1 regulates myoblast response to HGF via Met in a lipid raft-dependent mechanism: effect on migration of skeletal muscle precursor cellsThe mitogenic activity of fibroblast growth factor-1 correlates with its internalization and limited proteolytic processing.The NH2-terminal extension of high molecular weight forms of basic fibroblast growth factor (bFGF) is not essential for the binding of bFGF to nuclear chromatin in transfected NIH 3T3 cells.Characterization of fibroblast growth factor-2 binding to ribosomes.A novel tetracyclic peptide, trapoxin, induces phenotypic change from transformed to normal in sis-oncogene-transformed NIH3T3 cells.Transfection of cells with basic fibroblast growth factor and Kaposi fibroblast growth factor genes induce resistance to and receptor modulation of tumor necrosis factor.Fibroblast growth factor receptor-1 expression is associated with neointimal formation in vitro.New observations on the intracellular localization and release of bFGF.Expression of modified bFGF cDNAs in mammalian cells.Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix.A mutant of basic fibroblast growth factor that has lost the ability to stimulate plasminogen activator synthesis in endothelial cells.Fixed higher dose schedule of suramin plus hydrocortisone in patients with hormone refractory prostate carcinoma a multicenter Phase II study.Development of the vasculature of the anterior pituitary: ontogeny of basic fibroblast growth factor.
P2860
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P2860
Transformation of NIH 3T3 cells with basic fibroblast growth factor or the hst/K-fgf oncogene causes downregulation of the fibroblast growth factor receptor: reversal of morphological transformation and restoration of receptor number by suramin.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Transformation of NIH 3T3 cell ...... of receptor number by suramin.
@ast
Transformation of NIH 3T3 cell ...... of receptor number by suramin.
@en
type
label
Transformation of NIH 3T3 cell ...... of receptor number by suramin.
@ast
Transformation of NIH 3T3 cell ...... of receptor number by suramin.
@en
prefLabel
Transformation of NIH 3T3 cell ...... of receptor number by suramin.
@ast
Transformation of NIH 3T3 cell ...... of receptor number by suramin.
@en
P2860
P356
P1476
Transformation of NIH 3T3 cell ...... of receptor number by suramin
@en
P2093
P2860
P304
P356
10.1083/JCB.109.5.2519
P407
P577
1989-11-01T00:00:00Z