Isolation and characterization of Chinese hamster ovary cell mutants defective in assembly of peroxisomes.
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Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assemblyMolecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10pTopogenesis of peroxisomal membrane protein requires a short, positively charged intervening-loop sequence and flanking hydrophobic segments. study using human membrane protein PMP34Phenotype-genotype relationships in peroxisome biogenesis disorders of PEX1-defective complementation group 1 are defined by Pex1p-Pex6p interactionMutations in the peroxin Pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and interaction with the Pex1p x Pex6p complexTwo proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrixIn vitro transport of membrane proteins to peroxisomes by shuttling receptor Pex19pDynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26pCharacterization of the interaction between recombinant human peroxin Pex3p and Pex19p: identification of TRP-104 IN Pex3p as a critical residue for the interactionThe membrane biogenesis peroxin Pex16p. Topogenesis and functional roles in peroxisomal membrane assemblyThe peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathwayPEX12 encodes an integral membrane protein of peroxisomesClofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12pMutations in novel peroxin gene PEX26 that cause peroxisome-biogenesis disorders of complementation group 8 provide a genotype-phenotype correlationHsp70 regulates the interaction between the peroxisome targeting signal type 1 (PTS1)-receptor Pex5p and PTS1Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants.PEX3 is the causal gene responsible for peroxisome membrane assembly-defective Zellweger syndrome of complementation group G.Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import.The peroxin pex3p initiates membrane assembly in peroxisome biogenesisHuman PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group IA unified nomenclature for peroxisome biogenesis factorsCrystal structure of the conserved N-terminal domain of the peroxisomal matrix protein import receptor, Pex14pPAS3, a Saccharomyces cerevisiae gene encoding a peroxisomal integral membrane protein essential for peroxisome biogenesis.Peroxisomal membrane proteins insert into the endoplasmic reticulum.The peroxin Pex14p. cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysisCatalase-less peroxisomes. Implication in the milder forms of peroxisome biogenesis disorderPeroxisome assembly factor-2, a putative ATPase cloned by functional complementation on a peroxisome-deficient mammalian cell mutantCorrection by gene expression of biochemical abnormalities in fibroblasts from Zellweger patientsAWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPasePeroxisome assembly factor 1: nonsense mutation in a peroxisome-deficient Chinese hamster ovary cell mutant and deletion analysisTopogenesis and homeostasis of fatty acyl-CoA reductase 1Cysteine ubiquitination of PTS1 receptor Pex5p regulates Pex5p recycling.A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes.Peroxisome biogenesis and peroxisome biogenesis disorders.Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export.The membrane peroxin PEX3 induces peroxisome-ubiquitination-linked pexophagy.A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum.Import of proteins into peroxisomes and other microbodies.
P2860
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P2860
Isolation and characterization of Chinese hamster ovary cell mutants defective in assembly of peroxisomes.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh
1990年學術文章
@zh-hant
name
Isolation and characterization ...... ve in assembly of peroxisomes.
@ast
Isolation and characterization ...... ve in assembly of peroxisomes.
@en
type
label
Isolation and characterization ...... ve in assembly of peroxisomes.
@ast
Isolation and characterization ...... ve in assembly of peroxisomes.
@en
prefLabel
Isolation and characterization ...... ve in assembly of peroxisomes.
@ast
Isolation and characterization ...... ve in assembly of peroxisomes.
@en
P2093
P2860
P356
P1476
Isolation and characterization ...... ve in assembly of peroxisomes.
@en
P2093
P2860
P304
P356
10.1083/JCB.110.3.651
P407
P577
1990-03-01T00:00:00Z