Integrin signaling is critical for pathological angiogenesis - Wikidata - awgldk - TriplyDB

Integrin signaling is critical for pathological angiogenesis

Integrin signaling is critical for pathological angiogenesis

http://www.wikidata.org/entity/Q36228035

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Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesis αV integrins in angiogenesis and cancer FOSL1 controls the assembly of endothelial cells into capillary tubes by direct repression of αv and β3 integrin transcription The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression Integrin β3 crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities Mechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis.The integrin coactivator kindlin-2 plays a critical role in angiogenesis in mice and zebrafish Pathogenic hantaviruses direct the adherence of quiescent platelets to infected endothelial cells.Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent.Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis.Integrins as "functional hubs" in the regulation of pathological angiogenesis Dissection of platelet and myeloid cell defects by conditional targeting of the beta3-integrin subunit.c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin.Partial pulmonary embolization disrupts alveolarization in fetal sheep.Role of renal microcirculation in experimental renovascular disease.Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response Latent KSHV infection of endothelial cells induces integrin beta3 to activate angiogenic phenotypes A systems approach to hemostasis: 3. Thrombus consolidation regulates intrathrombus solute transport and local thrombin activity.Nanofiber Microenvironment Effectively Restores Angiogenic Potential of Diabetic Endothelial Cells.Integrins and bone metastasis: integrating tumor cell and stromal cell interactions.Why integrin as a primary target for imaging and therapy.Targeting of α(v)-integrins in stem/progenitor cells and supportive microenvironment impairs bone metastasis in human prostate cancer.Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner.Development of a chimeric recombinant disintegrin as a cost-effective anti-cancer agent with promising translational potential.Rac2 controls tumor growth, metastasis and M1-M2 macrophage differentiation in vivo.Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃.Interaction of kindlin-2 with integrin β3 promotes outside-in signaling responses by the αVβ3 vitronectin receptor Regulation of endothelial cell activation and angiogenesis by injectable peptide nanofibers.RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating α(v)β₃ expression The aortic ring model of angiogenesis: a quarter century of search and discovery.Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane.ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2.Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin.Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3 Integrin and VEGF Receptors The role of extracellular matrix in vascular branching morphogenesis EGFRvIII/integrin β3 interaction in hypoxic and vitronectinenriching microenvironment promote GBM progression and metastasis.Pathogenic angiogenesis in IBD and experimental colitis: new ideas and therapeutic avenues.Vascular endothelial-cadherin stimulates syndecan-1-coupled insulin-like growth factor-1 receptor and cross-talk between αVβ3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenes

P2860

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P2860

Integrin signaling is critical for pathological angiogenesis

http://www.wikidata.org/entity/Q36228035

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

Integrin signaling is critical for pathological angiogenesis

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Integrin signaling is critical for pathological angiogenesis

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type

label

Integrin signaling is critical for pathological angiogenesis

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Integrin signaling is critical for pathological angiogenesis

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prefLabel

Integrin signaling is critical for pathological angiogenesis

@ast

Integrin signaling is critical for pathological angiogenesis

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P1433

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Journal of Experimental Medicine

P1476

Integrin signaling is critical for pathological angiogenesis

@en

P2093

David R Phillips

http://www.w3.org/2001/XMLSchema#string

Ganapati H Mahabeleshwar

http://www.w3.org/2001/XMLSchema#string

Tatiana V Byzova

http://www.w3.org/2001/XMLSchema#string

Weiyi Feng

http://www.w3.org/2001/XMLSchema#string

P2860

Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

Endothelial integrins and angiogenesis: not so simple anymore

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

Integrins: bidirectional, allosteric signaling machines

Genetic compensation for sarcoglycan loss by integrin alpha7beta1 in muscle

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Requirement of vascular integrin alpha v beta 3 for angiogenesis

The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development.

Osteopontin induces AP-1-mediated secretion of urokinase-type plasminogen activator through c-Src-dependent epidermal growth factor receptor transactivation in breast cancer cells.

Integrin and growth factor receptor crosstalk.

P304

2495-2507

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scholarly article

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10.1084/JEM.20060807

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11

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203

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2006-10-09T00:00:00Z

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6764164

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17030947

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2118124

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