Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice. - Wikidata - awgldk - TriplyDB

Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice.

Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice.

http://www.wikidata.org/entity/Q36228990

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Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning The genetics of pulmonary arterial hypertension Caveolin-1 Deletion Prevents Hypertensive Vascular Remodeling Induced by Angiotensin II.Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX).Regulation of cellular communication by signaling microdomains in the blood vessel wall.Inhibition of renal caveolin-1 reduces natriuresis and produces hypertension in sodium-loaded rats.Endothelial caveolin-1 regulates pathologic angiogenesis in a mouse model of colitis.Endothelial Caveolin-1 regulates the radiation response of epithelial prostate tumors.Differential dependence of stretch and shear stress signaling on caveolin-1 in the vascular wall.Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase.Cardiac function is not significantly diminished in hearts isolated from young caveolin-1 knockout mice.Postobstructive regeneration of kidney is derailed when surge in renal stem cells during course of unilateral ureteral obstruction is halted.Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1.Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II.Chromosomal abnormalities among children born with conotruncal cardiac defects.Heritable forms of pulmonary arterial hypertension.Pulmonary hypertension and metabolic syndrome: Possible connection, PPARγ and Caveolin-1 Quantitative proteomics of caveolin-1-regulated proteins: characterization of polymerase i and transcript release factor/CAVIN-1 IN endothelial cells The role of caveolae in endothelial cell dysfunction with a focus on nutrition and environmental toxicants High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness Distinct roles of endothelial and adipocyte caveolin-1 in macrophage infiltration and adipose tissue metabolic activity.Eph-B4 prevents venous adaptive remodeling in the adult arterial environment.Carbon monoxide prevents ventilator-induced lung injury via caveolin-1.Cell-specific dual role of caveolin-1 in pulmonary hypertension.Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension Real-time dynamic movement of caveolin-1 during smooth muscle contraction of human colon and aged rat colon transfected with caveolin-1 cDNA Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF.Lipid raft redox signaling: molecular mechanisms in health and disease.Caveolin-1 prevents sustained angiotensin II-induced resistance artery constriction and obesity-induced high blood pressure.The potential protective role of caveolin-1 in intestinal inflammation in TNBS-induced murine colitis.Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids A noninhibitory mutant of the caveolin-1 scaffolding domain enhances eNOS-derived NO synthesis and vasodilation in mice.Cooperative role of caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase-mediated negative regulation of c-Src.Suppression of eNOS-derived superoxide by caveolin-1: a biopterin-dependent mechanism Plasminogen activator inhibitor-1 suppresses profibrotic responses in fibroblasts from fibrotic lungs Alteration of developmental and pathological retinal angiogenesis in angptl4-deficient mice.Altered membrane lipid domains limit pulmonary endothelial calcium entry following chronic hypoxia Role of caveolin-1 in endothelial BKCa channel regulation of vasoreactivity.Telmisartan regresses left ventricular hypertrophy in caveolin-1-deficient mice.Caveolae, caveolins, cavins, and endothelial cell function: new insights.

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P2860

Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice.

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Frank J Giordano

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Jun Yu

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Michelle I Lin

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Phillip Michael Bauer

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Takahisa Murata

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William C Sessa

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Yan Huang

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P2860

Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor

Caveolin-2 localizes to the golgi complex but redistributes to plasma membrane, caveolae, and rafts when co-expressed with caveolin-1

Caveolae and caveolins in the cardiovascular system

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts

Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae.

Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells

Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities

Disruption of caveolin-1 leads to enhanced nitrosative stress and severe systolic and diastolic heart failure

Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin

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