Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection - Wikidata - awgldk - TriplyDB

Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection

Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection

http://www.wikidata.org/entity/Q36229666

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Emerging concepts in the immunopathogenesis of AIDS The lymph node in HIV pathogenesis Nonpathogenic simian immunodeficiency virus infections Host-pathogen interaction in HIV infection T memory stem cells and HIV: a long-term relationship Natural SIV hosts: showing AIDS the door A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo Comparative Analysis of Immune Activation Markers of CD8(+) T Cells in Lymph Nodes of Different Origins in SIV-Infected Chinese Rhesus Macaques Functional impairment of central memory CD4 T cells is a potential early prognostic marker for changing viral load in SHIV-infected rhesus macaques Life and death as a T lymphocyte: from immune protection to HIV pathogenesis Association of differentiation state of CD4+ T cells and disease progression in HIV-1 perinatally infected children Modeling the Slow CD4+ T Cell Decline in HIV-Infected Individuals Recent Insights into the HIV/AIDS Pandemic.A mechanistic model for bromodeoxyuridine dilution naturally explains labelling data of self-renewing T cell populations.Dynamics of immune reconstitution and activation markers in HIV+ treatment-naïve patients treated with raltegravir, tenofovir disoproxil fumarate and emtricitabine Toll-like receptor ligands induce human T cell activation and death, a model for HIV pathogenesis.Immunopathogenesis of simian immunodeficiency virus infection in nonhuman primates Association of progressive CD4(+) T cell decline in SIV infection with the induction of autoreactive antibodies In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection.HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections.Extralymphoid CD8+ T cells resident in tissue from simian immunodeficiency virus SIVmac239{Delta}nef-vaccinated macaques suppress SIVmac239 replication ex vivo.A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.Adenovirus prime, Env protein boost vaccine protects against neutralization-resistant SIVsmE660 variants in rhesus monkeys.Monitoring of NY-ESO-1 specific CD4+ T cells using molecularly defined MHC class II/His-tag-peptide tetramers.A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation Altered T cell memory and effector cell development in chronic lymphatic filarial infection that is independent of persistent parasite antigen.Cytomegalovirus-specific responses of CD38⁺ memory T cells are skewed towards IFN-γ and dissociated from CD154 in HIV-1 infection Differential MHC class I expression in distinct leukocyte subsets NY-ESO-1-specific circulating CD4+ T cells in ovarian cancer patients are prevalently T(H)1 type cells undetectable in the CD25+ FOXP3+ Treg compartment.HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+ T cells Nonprogressive and progressive primate immunodeficiency lentivirus infections.S-phase entry leads to cell death in circulating T cells from HIV-infected persons.Interleukin-7 receptor signaling is deficient in CD4+ T cells from HIV-infected persons and is inversely associated with aging.Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates.Memory phenotype CD4 T cells undergoing rapid, nonburst-like, cytokine-driven proliferation can be distinguished from antigen-experienced memory cells Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals.Reconstitution of CD4 T cells in bronchoalveolar lavage fluid after initiation of highly active antiretroviral therapy.Immunologic and virologic events in early HIV infection predict subsequent rate of progression.Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells.

P2860

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P2860

Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection

http://www.wikidata.org/entity/Q36229666

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2007 nî lūn-bûn

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2007年論文

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Progressive CD4+ central memor ...... sease in chronic SIV infection

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Journal of Experimental Medicine

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Progressive CD4+ central memor ...... sease in chronic SIV infection

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P2093

Afam Okoye

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Alfred Legasse

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Andrew W Sylwester

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Daniel C Douek

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Donald L Sodora

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Jason M Brenchley

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Jeffrey D Lifson

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John B Edgar

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Louis J Picker

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Martin Meier-Schellersheim

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P2860

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates

Pathogenesis of human immunodeficiency virus infection

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

HIV/AIDS epidemiology, pathogenesis, prevention, and treatment

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2171-2185

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10.1084/JEM.20070567

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9

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204

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Joshua M. Walker

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2007-08-27T00:00:00Z

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6116446

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17724130

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2118701

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