Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties
about
Cytoplasmic tail regulates the intercellular adhesion function of the epithelial cell adhesion moleculeIntegrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1.Tyrosine residue in exon 14 of the cytoplasmic domain of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) regulates ligand binding specificityA novel protein with homology to the junctional adhesion molecule. Characterization of leukocyte interactionsRegulation of mouse PECAM-1 tyrosine phosphorylation by the Src and Csk families of protein-tyrosine kinasesThe carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cellsThe protein-tyrosine phosphatase SHP-2 associates with tyrosine-phosphorylated adhesion molecule PECAM-1 (CD31)Aggregation of the high affinity IgE receptor results in the tyrosine phosphorylation of the surface adhesion protein PECAM-1 (CD31)CD31/PECAM-1 is a ligand for alpha v beta 3 integrin involved in adhesion of leukocytes to endotheliumPECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in CisPreeclampsia does not alter vascular growth and expression of CD31 and vascular endothelial cadherin in human placentasPlatelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) tyrosine phosphorylation state changes during vasculogenesis in the murine conceptusDevelopmental platelet endothelial cell adhesion molecule expression suggests multiple roles for a vascular adhesion molecule.PECAM-1, apoptosis and CD34+ precursors.A role for the alphavbeta3 integrin in the transmigration of monocytes.T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesisMigration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesisRhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1.The biology of PECAM-1.Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin releaseAlternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1).Characterization of an apparently conserved epitope in E- and P-selectin identified by dual-specific monoclonal antibodies.The Lutheran blood group glycoproteins, the erythroid receptors for laminin, are adhesion molecules.Interaction of CD31 with a heterophilic counterreceptor involved in downregulation of human T cell responses.The cytoplasmic domain of the alpha-subunit of glycoprotein (GP) Ib mediates attachment of the entire GP Ib-IX complex to the cytoskeleton and regulates von Willebrand factor-induced changes in cell morphology.Down-regulation of platelet endothelial cell adhesion molecule-1 results in thrombospondin-1 expression and concerted regulation of endothelial cell phenotype.ICAM-2 confers a non-metastatic phenotype in neuroblastoma cells by interaction with α-actinin.The cytoplasmic domain of the Drosophila cell adhesion molecule neuroglian is not essential for its homophilic adhesive properties in S2 cells.Influence of PECAM-1 ligand interactions on PECAM-1-dependent cell motility and filopodia extensionThrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis.PECAM-1: its expression and function as a cell adhesion molecule on hemopoietic and endothelial cells.Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity.Mapping the homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contacts.The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31).Synthetic matrix metalloproteinase inhibitor, BB-94, inhibits the invasion of neoplastic human prostate cells in a mouse model.CRISPR-mediated deletion of the PECAM-1 cytoplasmic domain increases receptor lateral mobility and strengthens endothelial cell junctional integrity.
P2860
Q24522613-607F5D2A-D5F6-48CE-9640-F549E8BD3029Q24603757-79A8E47D-65D8-4206-952F-12367BFE10A5Q24683731-FD20193A-BED2-4992-B582-A5BF63EBEDC6Q28143886-54A0E7B4-1F3B-4B63-A1BD-624E6E3B8EF2Q28273557-D04B44BB-3FD6-4265-9349-BC442D2A9EBEQ28292434-A31E67FF-EB84-4D95-B9DD-CC9043B247B5Q28566441-A90386AC-8F40-4462-B9C2-A2BB1066D0E8Q28581208-C8DC70E9-2810-4F3B-BE91-AB4365C4C3F7Q28647276-5ED121F8-75F8-4FC9-9E10-76A25B1C29E8Q34758185-F9A90515-2102-4F77-8B4C-4C383D4FB5EDQ35401872-1A04BAEC-53C8-467E-B489-7FA6C1E9E2A1Q35764482-34997523-56DB-4B37-ABF9-E5D04979C40BQ35786776-5C05BA41-995F-4C1B-8DC3-A1C6A19A7C46Q35932028-02342B17-08A7-4695-909D-3FDAF1552739Q36256245-05C1657D-085D-4AC9-8C75-62A1A7ACE54CQ36363699-61D0C8C7-EE9E-4DCF-9376-117A6340DCF0Q36365479-F42F3DCC-ECAD-40DE-A303-E94B003379C8Q36473318-01E7B8A4-3C01-4888-B1EB-3F687D24EE1EQ36491844-2E030E5B-9062-471B-AB2B-0BF9AB5F2822Q37362238-6962236F-D18D-4C6A-B8BD-B35429293008Q37377050-27E6CB56-8328-4B33-B981-62E62B0B86A6Q38290572-BA919C39-7A7A-4A2A-ADB0-E5C4B9FBCDCBQ38324010-5B06641F-8BCD-4FA6-AF49-1D21721F7802Q38336122-40BD115D-25B9-4019-8258-7985DDFF7A51Q38356006-82018631-A0AA-4EF0-A44A-381C941AA37EQ38357855-E6BFC958-A9AB-490F-A4C6-96B58EB30B52Q38611003-180837ED-55F2-49A2-A89C-CA643ACB907AQ39007416-1F6B2032-67DA-4CD6-ACC6-39509F997232Q39111017-98872790-F24D-4C86-BC9A-F325E207036BQ39147388-982CC5AE-580A-4F0E-8EF4-7341FBFDCD09Q40243674-979FC6AA-7537-4839-8DA4-641E7C8DB61CQ40958086-2C82B5D4-2475-43A8-B7D3-FEACBDE495F9Q41199320-46864F56-E991-4532-8CCC-C679052D215AQ41844323-C5897925-0E00-4DEA-AA64-91B1803D4981Q42152390-6F66C0C4-A0FA-40DF-941D-6EB6AE1B566BQ42456038-25EE4F3B-3F9D-4D63-AC9F-B707547B9A25Q47419832-18FF455F-57E7-4A15-AD53-B20B4808D487
P2860
Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Deletions in the cytoplasmic d ...... s in ligand binding properties
@ast
Deletions in the cytoplasmic d ...... s in ligand binding properties
@en
type
label
Deletions in the cytoplasmic d ...... s in ligand binding properties
@ast
Deletions in the cytoplasmic d ...... s in ligand binding properties
@en
prefLabel
Deletions in the cytoplasmic d ...... s in ligand binding properties
@ast
Deletions in the cytoplasmic d ...... s in ligand binding properties
@en
P2093
P2860
P356
P1476
Deletions in the cytoplasmic d ...... s in ligand binding properties
@en
P2093
H M DeLisser
J Chilkotowsky
S M Albelda
P2860
P304
P356
10.1083/JCB.124.1.195
P407
P577
1994-01-01T00:00:00Z