Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading and migration, and matrix assembly.
about
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting proteinAnthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeletonICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrinThe zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transitionp190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linkingCharacterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cellsVE-cadherin regulates endothelial actin activating Rac and increasing membrane association of TiamSite-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis.Activity-dependent regulation of synaptic AMPA receptor composition and abundance by beta3 integrinsCellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cellsAffinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tailThe phosphotyrosine binding-like domain of talin activates integrinsThe sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA bindingBeta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cellsA novel beta 1 integrin isoform produced by alternative splicing: unique expression in cardiac and skeletal muscleSpecific association of CD63 with the VLA-3 and VLA-6 integrinsMolecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatographyThe role of conserved amino acid motifs within the integrin beta3 cytoplasmic domain in triggering focal adhesion kinase phosphorylationGreen fluorescent protein (GFP) tagged to the cytoplasmic tail of alphaIIb or beta3 allows the expression of a fully functional integrin alphaIIb(beta3): effect of beta3GFP on alphaIIb(beta3) ligand bindingThe oligodendrocyte precursor mitogen PDGF stimulates proliferation by activation of alpha(v)beta3 integrins.The Fat1 cadherin integrates vascular smooth muscle cell growth and migration signalsCadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization.Primary megakaryocytes reveal a role for transcription factor NF-E2 in integrin alpha IIb beta 3 signalingRegulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanismCardiac expression of a gain-of-function alpha(5)-integrin results in perinatal lethality.Disruption of C-terminal cytoplasmic domain of betaPS integrin subunit has dominant negative properties in developing Drosophila.Growth defects induced by perturbation of beta1-integrin function in the mammary gland epithelium result from a lack of MAPK activation via the Shc and Akt pathways.Perturbation of beta1-integrin function alters the development of murine mammary gland.The cytoplasmic tyrosines of integrin subunit beta1 are involved in focal adhesion kinase activationBeta1 integrins mediate mechanosensitive signaling pathways in osteocytesQuantitative morphodynamics of endothelial cells within confluent cultures in response to fluid shear stressPlakoglobin rescues adhesive defects induced by ectodomain truncation of the desmosomal cadherin desmoglein 1: implications for exfoliative toxin-mediated skin blistering.Integrin beta 1 cytoplasmic domain dominant negative effects revealed by lysophosphatidic acid treatment.Specialized functional properties of the integrin alpha 4 cytoplasmic domain.Signaling dependent and independent mechanisms in pemphigus vulgaris blister formationDeath effector domain protein PEA-15 potentiates Ras activation of extracellular signal receptor-activated kinase by an adhesion-independent mechanismSuppression of tumor angiogenesis through the inhibition of integrin function and signaling in endothelial cells: which side to target?Beta1C integrin in epithelial cells correlates with a nonproliferative phenotype: forced expression of beta1C inhibits prostate epithelial cell proliferation.P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin
P2860
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P2860
Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading and migration, and matrix assembly.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Single subunit chimeric integr ...... igration, and matrix assembly.
@ast
Single subunit chimeric integr ...... igration, and matrix assembly.
@en
type
label
Single subunit chimeric integr ...... igration, and matrix assembly.
@ast
Single subunit chimeric integr ...... igration, and matrix assembly.
@en
prefLabel
Single subunit chimeric integr ...... igration, and matrix assembly.
@ast
Single subunit chimeric integr ...... igration, and matrix assembly.
@en
P2093
P2860
P356
P1476
Single subunit chimeric integr ...... igration, and matrix assembly.
@en
P2093
P2860
P304
P356
10.1083/JCB.126.5.1287
P407
P577
1994-09-01T00:00:00Z