about
The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conservedEukaryotic DNA polymerase ζCharacterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacityDNA polymerases at the eukaryotic fork-20 years laterHypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.Engineering processive DNA polymerases with maximum benefit at minimum costError-prone polymerase activity causes multinucleotide mutations in humans.In vivo bypass of 8-oxodG.Fragile DNA motifs trigger mutagenesis at distant chromosomal loci in saccharomyces cerevisiae.Mutator phenotypes due to DNA replication infidelity.Lesion bypass by S. cerevisiae Pol ζ alone.Role of AtPolζ, AtRev1 and AtPolη in γ ray-induced mutagenesisAltered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity.Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.DNA polymerase ζ generates tandem mutations in immunoglobulin variable regionsAn APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancersEvolving views of DNA replication (in)fidelity.DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae.The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases delta and eta.An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers.Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase zeta.The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7,8-dihydro-8-oxoguanine in yeast.PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}.Regulation of recombination and genomic maintenance.Polymerase ζ Activity Is Linked to Replication Timing in Humans: Evidence from Mutational Signatures.Activation of Dun1 in response to nuclear DNA instability accounts for the increase in mitochondrial point mutations in Rad27/FEN1 deficient S. cerevisiae.Phenotypic diversification by enhanced genome restructuring after induction of multiple DNA double-strand breaks.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mutator alleles of yeast DNA polymerase zeta.
@ast
Mutator alleles of yeast DNA polymerase zeta.
@en
type
label
Mutator alleles of yeast DNA polymerase zeta.
@ast
Mutator alleles of yeast DNA polymerase zeta.
@en
prefLabel
Mutator alleles of yeast DNA polymerase zeta.
@ast
Mutator alleles of yeast DNA polymerase zeta.
@en
P2093
P2860
P1433
P1476
Mutator alleles of yeast DNA polymerase zeta
@en
P2093
Ayako N Sakamoto
Grace E Kissling
Jana E Stone
Scott D McCulloch
Youri I Pavlov
P2860
P304
P356
10.1016/J.DNAREP.2007.07.002
P577
2007-08-21T00:00:00Z