Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity.
about
Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2.Autoreactivity in HIV-1 broadly neutralizing antibodies: implications for their function and induction by vaccination.Error-prone polymerase activity causes multinucleotide mutations in humans.Opinion: uracil DNA glycosylase (UNG) plays distinct and non-canonical roles in somatic hypermutation and class switch recombination.APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination.Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerasesDual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses.DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae.DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genesEvaluation of the Antigen-Experienced B-Cell Receptor Repertoire in Healthy Children and AdultsA missense mutation in Rev7 disrupts formation of Polζ, impairing mouse development and repair of genotoxic agent-induced DNA lesions.Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass.Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylaseHuman Ig knockin mice to study the development and regulation of HIV-1 broadly neutralizing antibodies.Induction of action-at-a-distance mutagenesis by 8-oxo-7,8-dihydroguanine in DNA pol λ-knockdown cells.Diversity in the Cow Ultralong CDR H3 Antibody Repertoire.
P2860
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P2860
Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Altered Ig hypermutation patte ...... of DNA polymerase ζ activity.
@ast
Altered Ig hypermutation patte ...... of DNA polymerase ζ activity.
@en
type
label
Altered Ig hypermutation patte ...... of DNA polymerase ζ activity.
@ast
Altered Ig hypermutation patte ...... of DNA polymerase ζ activity.
@en
prefLabel
Altered Ig hypermutation patte ...... of DNA polymerase ζ activity.
@ast
Altered Ig hypermutation patte ...... of DNA polymerase ζ activity.
@en
P2093
P2860
P356
P1476
Altered Ig hypermutation patte ...... of DNA polymerase ζ activity.
@en
P2093
Chuancang Jiang
Danielle L Watt
Janssen Daly
Katarzyna Bebenek
Kathleen Richter
Madhumita Ray
Marilyn Diaz
Ming-Lang Zhao
Thomas A Kunkel
W Glenn McGregor
P2860
P304
P356
10.4049/JIMMUNOL.1102629
P407
P577
2012-04-30T00:00:00Z