Nuclear factories for signalling and repairing DNA double strand breaks in living fission yeast.
about
The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machineryLong patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complexReal-time imaging of DNA damage in yeast cells using ultra-short near-infrared pulsed laser irradiationFission yeast Rad52 phosphorylation restrains error prone recombination pathwaysReplication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast.A comprehensive faculty, staff, and student training program enhances student perceptions of a course-based research experience at a two-year institutionViral transport of DNA damage that mimics a stalled replication fork.The fission yeast DNA structure checkpoint protein Rad26ATRIP/LCD1/UVSD accumulates in the cytoplasm following microtubule destabilizationA DNA polymerase alpha accessory protein, Mcl1, is required for propagation of centromere structures in fission yeastRgf1p (Rho1p GEF) is required for double-strand break repair in fission yeast.Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast.Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage.Genome-wide mapping of nuclear mitochondrial DNA sequences links DNA replication origins to chromosomal double-strand break formation in Schizosaccharomyces pombe.Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeastStress activated protein kinase pathway modulates homologous recombination in fission yeastRqh1 blocks recombination between sister chromatids during double strand break repair, independent of its helicase activity.CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR.Developmental control of late replication and S phase lengthUltrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier.Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response MutantsThe human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repairKu stabilizes replication forks in the absence of Brc1.Aneuploidy drives genomic instability in yeast.The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta in long patch base excision repairThe human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates NEIL1 glycosylaseAbundance of prereplicative complexes (Pre-RCs) facilitates recombinational repair under replication stress in fission yeastThe Caenorhabditis elegans Rad17 homolog HPR-17 is required for telomere replication.Microhomology-mediated DNA strand annealing and elongation by human DNA polymerases λ and β on normal and repetitive DNA sequences.Temporal separation of replication and recombination requires the intra-S checkpoint.A drug-compatible and temperature-controlled microfluidic device for live-cell imaging.PCNA promotes processive DNA end resection by Exo1.The checkpoint-dependent nuclear accumulation of Rho1p exchange factor Rgf1p is important for tolerance to chronic replication stressThe dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease.Homologous recombination as a replication fork escort: fork-protection and recovery.Cds1 controls the release of Cdc14-like phosphatase Flp1 from the nucleolus to drive full activation of the checkpoint response to replication stress in fission yeast.Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapseThe IGH locus relocalizes to a "recombination compartment" in the perinucleolar region of differentiating B-lymphocytes.Replication fork collapse and genome instability in a deoxycytidylate deaminase mutant.Fbh1 limits Rad51-dependent recombination at blocked replication forks.TORC2 is required to maintain genome stability during S phase in fission yeast.
P2860
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P2860
Nuclear factories for signalling and repairing DNA double strand breaks in living fission yeast.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Nuclear factories for signalli ...... reaks in living fission yeast.
@ast
Nuclear factories for signalli ...... reaks in living fission yeast.
@en
type
label
Nuclear factories for signalli ...... reaks in living fission yeast.
@ast
Nuclear factories for signalli ...... reaks in living fission yeast.
@en
prefLabel
Nuclear factories for signalli ...... reaks in living fission yeast.
@ast
Nuclear factories for signalli ...... reaks in living fission yeast.
@en
P2093
P2860
P356
P1476
Nuclear factories for signalli ...... breaks in living fission yeast
@en
P2093
Giuseppe Baldacci
Isabelle Tratner
Mickaël Poidevin
Patrick Zarzov
Stefania Francesconi
P2860
P304
P356
10.1093/NAR/GKG719
P407
P577
2003-09-01T00:00:00Z