Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex
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SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpointCritical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpointDNA Damage Response and Immune Defense: Links and MechanismsTargeting the Checkpoint to Kill Cancer CellsXrs2p regulates Mre11p translocation to the nucleus and plays a role in telomere elongation and meiotic recombination.Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast.Mutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae.Protein phosphatases pph3, ptc2, and ptc3 play redundant roles in DNA double-strand break repair by homologous recombination.A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair.MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae.A physical and functional interaction between yeast Pol4 and Dnl4-Lif1 links DNA synthesis and ligation in nonhomologous end joining.DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.Interaction of FANCD2 and NBS1 in the DNA damage responseHyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression.ZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing overSaccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activitiesRole of RAD52 epistasis group genes in homologous recombination and double-strand break repairSite-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1Genetic variation in the NBS1, MRE11, RAD50 and BLM genes and susceptibility to non-Hodgkin lymphoma.Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint.The genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1.Cdk1-dependent regulation of the Mre11 complex couples DNA repair pathways to cell cycle progressionHuman MRE11 is inactivated in mismatch repair-deficient cancers.Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae.NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sitesA genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damageInitiation of DNA damage responses through XPG-related nucleasesMutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activityGenetic and physical interactions between DPB11 and DDC1 in the yeast DNA damage response pathwayKu-dependent and Ku-independent end-joining pathways lead to chromosomal rearrangements during double-strand break repair in Saccharomyces cerevisiae.Positive and negative roles of homologous recombination in the maintenance of genome stability in Saccharomyces cerevisiae.Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.Short telomeres induce a DNA damage response in Saccharomyces cerevisiae.Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeastThe Mre11-Rad50-Xrs2 complex is required for yeast DNA postreplication repairCancer predisposition and hematopoietic failure in Rad50(S/S) mice.ATP-dependent chromatin remodeling factors and DNA damage repairChecking on DNA damage in S phase.Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance
P2860
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P2860
Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@ast
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@en
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@nl
type
label
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@ast
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@en
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@nl
prefLabel
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@ast
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@en
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@nl
P3181
P356
P1433
P1476
Checkpoint activation in respo ...... s the Mre11/Rad50/Xrs2 complex
@en
P2093
P2888
P304
P3181
P356
10.1038/NCB0901-844
P407
P577
2001-09-01T00:00:00Z
P6179
1020395336