Cloning and characterization of Kluyveromyces lactis SEC14, a gene whose product stimulates Golgi secretory function in Saccharomyces cerevisiae.
about
Cloning and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14pRetinoid-binding proteins: mediators of retinoid actionStructural and functional characterization of recombinant human cellular retinaldehyde-binding proteinDimeric Sfh3 has structural changes in its binding pocket that are associated with a dimer-monomer state transformation induced by substrate bindingCrystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer proteinTrans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy.Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth.SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast.Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae.Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activityPhospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defectsConformational dynamics of the major yeast phosphatidylinositol transfer protein sec14p: insight into the mechanisms of phospholipid exchange and diseases of sec14p-like protein deficiencies.The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signalingPITPs as targets for selectively interfering with phosphoinositide signaling in cellsNovel developmentally regulated phosphoinositide binding proteins from soybean whose expression bypasses the requirement for an essential phosphatidylinositol transfer protein in yeastActivity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast.Mutant rat phosphatidylinositol/phosphatidylcholine transfer proteins specifically defective in phosphatidylinositol transfer: implications for the regulation of phospholipid transfer activity.The yeast BSD2-1 mutation influences both the requirement for phosphatidylinositol transfer protein function and derepression of phospholipid biosynthetic gene expression in yeast.Aggregation of α-synuclein in S. cerevisiae is associated with defects in endosomal trafficking and phospholipid biosynthesis.Evidence for an intrinsic toxicity of phosphatidylcholine to Sec14p-dependent protein transport from the yeast Golgi complex.Biological functions of phosphatidylinositol transfer proteins.Altered response to growth rate changes in Kluyveromyces lactis versus Saccharomyces cerevisiae as demonstrated by heterologous expression of ribosomal protein 59 (CRY1)Comparative Proteome Analysis in Schizosaccharomyces pombe Identifies Metabolic Targets to Improve Protein Production and Secretion.A phosphatidylinositol/phosphatidylcholine transfer protein is required for differentiation of the dimorphic yeast Yarrowia lipolytica from the yeast to the mycelial form.Phosphatidylinositol transfer proteins: negotiating the regulatory interface between lipid metabolism and lipid signaling in diverse cellular processes.Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate Golgi functionality.Cellular retinaldehyde-binding protein ligand interactions. Gln-210 and Lys-221 are in the retinoid binding pocket.Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains.Phospholipid transfer activity is relevant to but not sufficient for the essential function of the yeast SEC14 gene productAn isoform of the phosphatidylinositol-transfer protein transfers sphingomyelin and is associated with the Golgi system.Phosphorylation and redistribution of the phosphatidylinositol-transfer protein in phorbol 12-myristate 13-acetate- and bombesin-stimulated Swiss mouse 3T3 fibroblasts.Limited proteolysis of rat phosphatidylinositol transfer protein by trypsin cleaves the C terminus, enhances binding to lipid vesicles, and reduces phospholipid transfer activity.
P2860
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P2860
Cloning and characterization of Kluyveromyces lactis SEC14, a gene whose product stimulates Golgi secretory function in Saccharomyces cerevisiae.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
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name
Cloning and characterization o ...... n in Saccharomyces cerevisiae.
@ast
Cloning and characterization o ...... n in Saccharomyces cerevisiae.
@en
type
label
Cloning and characterization o ...... n in Saccharomyces cerevisiae.
@ast
Cloning and characterization o ...... n in Saccharomyces cerevisiae.
@en
prefLabel
Cloning and characterization o ...... n in Saccharomyces cerevisiae.
@ast
Cloning and characterization o ...... n in Saccharomyces cerevisiae.
@en
P2093
P2860
P1476
Cloning and characterization o ...... n in Saccharomyces cerevisiae.
@en
P2093
Bankaitis VA
Malehorn DE
Whitters EA
P2860
P304
P356
10.1128/JB.172.8.4510-4521.1990
P407
P577
1990-08-01T00:00:00Z